Rutin-Activated Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Attenuates Corneal and Heart Damage in Mice.

Corneal degeneration is a form of progressive cell death caused by multiple factors, such as diabetic retinopathy. It is the most well-known neural degenerative disease caused by macular degeneration in the aged and those with retinitis pigmentosa. Myocardial infarction is becoming a more common burden, causing cardiomyocyte degeneration, ischemia, and heart tissue death.

Metagenomic Analysis of Sediment Bacterial Diversity and Composition in Natural Lakes and Artificial Waterpoints of Tabuk Region in King Salman Bin Abdulaziz Royal Natural Reserve, Saudi Arabia.

The Tabuk region is located in the northern part of Saudi Arabia, and it has an area of 117,000 km between longitudes 26° N and 29° N and latitudes 34° E and 38° E. King Salman Bin Abdulaziz Royal Natural Reserve (KSRNR) is the largest natural reserve in Saudi Arabia and covers about 130,700 km. It represents a new tourist attraction area in the Tabuk region.

The Role of in the Pathogenesis of Corneal Ulcer, Its Associated Virulence Factors, and Suggested Novel Treatment Approaches.

Background: , is a diverse Gram-negative pathogen commonly associated with a wide spectrum of infections. It is indicated to be the most prevalent causative agent in the development of bacterial keratitis linked with the use of contact lens. Corneal infections attributed to frequently have poor clinical outcomes necessitating lengthy and costly therapies.

Anethole alleviates Doxorubicin-induced cardiac and renal toxicities: Insights from network pharmacology and animal studies.

Doxorubicin (Dox) is widely used as a chemotherapy drug, while anethole (AN) is primarily known as the main aromatic component in various plant species. This research focused on the impact of AN on the cardiac and renal toxicity induced by Dox and to understand the underlying mechanisms. For cardiac toxicity, Wistar rats were categorized into four groups: a Control group; a Dox group, where rats received 2.

The threat of microplastics: Exploring pollution in coastal ecosystems and migratory shorebirds along the west coast of India.

To evaluate the exposure risk and ingestion of microplastics by migratory shorebirds, which are regarded as apex predators in the coastal ecosystem, this study investigated the ubiquitous presence of microplastics in estuarine and coastal habitats and their potential to be transferred in the food chains. We analysed the presence of microplastics in water, sediment, major macroinvertebrate prey and the guano samples of ten shorebird species from ten important wintering grounds in the west coast of India. Our results revealed that water is the primary source through which microplastics disseminate into various ecosystem components.

Conservation action in Saudi Arabia: Challenges and opportunities.

The conservation of biological diversity is gaining an increasing amount of global attention. In particular, in Saudi Arabia, conservation actions have become a topic of focus, with many successful initiatives being implemented. Despite these efforts, several wild animal species in Saudi Arabia still require special attention to ensure their long-term conservation and survival.