Gut microbiota analyses of inflammatory bowel diseases from a representative Saudi population.

Background: Crohn's diseases and ulcerative colitis, both of which are chronic immune-mediated disorders of the gastrointestinal tract are major contributors to the overarching Inflammatory bowel diseases. It has become increasingly evident that the pathological processes of IBDs results from interactions between genetic and environmental factors, which can skew immune responses against normal intestinal flora.

Methods: The aim of this study is to assess and analyze the taxa diversity and relative abundances in CD and UC in the Saudi population.

Gut microbiota analyses of Saudi populations for type 2 diabetes-related phenotypes reveals significant association.

Background: Large-scale gut microbiome sequencing has revealed key links between microbiome dysfunction and metabolic diseases such as type 2 diabetes (T2D). To date, these efforts have largely focused on Western populations, with few studies assessing T2D microbiota associations in Middle Eastern communities where T2D prevalence is now over 20%. We analyzed the composition of stool 16S rRNA from 461 T2D and 119 non-T2D participants from the Eastern Province of Saudi Arabia.

Molecular characterization of clinical isolates from Eastern Saudi Arabia.

Objectives: To describe the frequency of () and () virulence genes and clarithromycin resistance-associated mutations among () clinical isolates from Eastern Saudi Arabia.

Methods: A cross-sectional study was carried out between July 2020 and June 2021 in a tertiary hospital in AL-Khobar, Saudi Arabia. A total of 34 isolates were obtained from gastric biopsies of patients with dyspepsia.

Obesity and gastric balloon.

Background: The obesity epidemic, which is among the most common nutritional disorders, is rising rapidly worldwide. It leads to several health problems such as metabolic disorders, stroke, and even cancer. Efforts to control obesity with exercise and diet have a limited value in obese patients and different approaches to do this have been tried.

The self-limiting nature of statin-induced rhabdomyolysis.

Statins have come to the forefront of treatments for hyperlipidemias, coronary artery diseases and strokes. They have been shown to cause myotoxicity and rhabdomyolysis. In most cases, rhabdomyolysis is self-limiting and needs supportive therapy.

Prevalence of gastroesophageal reflux disease and its association with Helicobacter pylori infection in chronic renal failure patients and in renal transplant recipients.

Background/aims: The prevalence of gastroesophageal reflux disease (GERD) in chronic renal failure patients and in renal transplant recipients (RTR) has been a subject of discussion in the last few years. Our aims are to clarify this association and its relation to Helicobacter pylori infection, and also to identify possible pathogenic factors in the development of this disease in both groups.

Methods: The study involved 40 end-stage renal disease (ESRD) patients with upper gastrointestinal (GI) symptoms (group I), 36 patients who had undergone kidney transplantation and had similar symptoms (group II), and 44 age- and sex-matched controls with the same upper GI symptoms (group III).

Coexisting malignant lymphoma of the duodenum and adenocarcinoma of the colon.

Synchronous malignant mucosa associated lymphoid tissue MALT-lymphoma of the small bowel and adenocarcinoma of the colon in the same patient is a scarce rarity. Only few cases have been reported so far. Thus, it might be of interest to report such a case of coexisting malignant MALT-lymphoma of the duodenum and adenocarcinoma of the large bowel.

Saphenoperitoneal shunt for intractable ascites.

Objective: Ascites usually complicates chronic liver disease, and some patients with ascites are refractory to medical treatment. Recently, saphenoperitoneal shunt (SPS) was described to treat this condition. This procedure avoids the insertion of a foreign expensive shunt into the circulation.

Gastric malignancy: clinicopathologic spectrum and relationship to Helicobacter pylori infection.

Background: Upper gastrointestinal cancer particularly of stomach is a relatively frequent form of cancer. Gastric H pylori infection has been implicated in the pathogenesis of both gastric carcinoma and gastric lymphoma. Gastric carcinoma has been addressed by many articles in the Kingdom of Saudi Arabia (KSA) and the Middle East, while only a few addressed gastric lymphoma.

Hospital generated waste: an assessment of the awareness of hospital staff.

Background: The provision of healthcare generates waste which can be detrimental to health and environment. Staff who provide healthcare ought to be aware of the proper handling and the system of management of healthcare waste used by different hospitals.

Materials And Methods: A survey of doctors, nurses and allied medical staff for their awareness of the hospital generation and handling of waste was conducted.