Publications by authors named "Abdul Manan Junejo"

Background Dialysis-associated morbidity and mortality among end-stage renal disease (ESRD) patients has been increasing, despite the advancement in pharmacological treatment and dialysis technology. The aim of this study was to determine the outcomes of dialysis among ESRD patients presenting at the nephrology department of Jinnah Postgraduate Medical Centre (JPMC).  Methodology This cross-sectional study was conducted during the year 2015-2016, including 105 ESRD patients.

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Article Synopsis
  • Hemodialysis is an important treatment for patients with end-stage renal disease (ESRD), allowing for a better quality of life, but it can lead to complications ranging from minor to life-threatening during the procedure.
  • A study conducted at Jinnah Postgraduate Medical Centre analyzed 94 patients, finding that the most common complication was hypotension, affecting 28.7% of patients, followed by hypertension (17%) and nausea/vomiting (11.7%).
  • The findings highlight the significance of monitoring blood pressure during hemodialysis, with plans for future research to further investigate acute and chronic complications related to dialysis.
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Objective: We aimed to compare the efficacy of gabapentin and levodopa-c for the symptoms of restless leg syndrome in patients of end-stage renal disease (ESRD) undergoing maintenance hemodialysis therapy.

Methods:  In this observational, cross-sectional study, patients of ESRD on hemodialysis with restless leg syndrome were included after assessment of symptoms and quality of sleep before the treatment by completing two questionnaires: the International Restless Leg Syndrome Study Group (IRLSSG) questionnaire and the Pittsburgh Sleep Quality Index (PSQI) scale. They were randomly divided into two groups.

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Article Synopsis
  • * A total of 230 patients were analyzed, mostly aged between 20-50 years, with sepsis being the leading cause of AKI (71.73%), and 66.96% of patients showed improvement post-treatment.
  • * The findings highlight the need for better hospital care to manage sepsis and reduce the risks of progression to chronic kidney disease and mortality in hospitalized patients.
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Objectives: To assess the association of hypovitaminosis D with diabetes mellitus (DM) in patients with end stage renal disease (ESRD) undergoing hemodialysis.

Methodology: This cross-sectional study was conducted at the Jinnah Postgraduate Medical Centre between July 2019 and February 2020. Patients with diagnosed ESRD who were on hemodialysis, with or without concomitant DM were registered.

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Objective: To evaluate association of serum visfatin with CKD secondary to diabetic nephropathy and to compare it with patients of CKD secondary to other risk factors.

Methods: Seventy eight individuals including 28 healthy controls and 50 patients of CKD were included in this study. Patients with CKD were further grouped based on etiology of CKD into diabetics and non-diabetics.

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Objective: To determine the etiology and outcome of Acute Renal Failure (ARF) in pregnancy.

Study Design: A case series.

Place And Duration Of Study: Nephrology Department of the Jinnah Postgraduate Medical Centre, Karachi, from August 2007 to July 2008.

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Background: Malaria has protean clinical manifestations and acute renal failure (ARF) is one of its serious complications and could be life threatening. This study was carried out to describe the clinical characteristics and factors associated with adverse out come in patients with malarial acute renal failure.

Methods: Data of 46 Patients with ARF and smear positive malaria was analyzed further among all cases of ARF presented to us at Nephrology department of Jinnah Postgraduate Medical Centre, Karachi from January 2003 to December 2004.

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