Partial least squares-discriminant analysis (PLS-DA) is a versatile algorithm that can be used for predictive and descriptive modelling as well as for discriminative variable selection. However, versatility is both a blessing and a curse and the user needs to optimize a wealth of parameters before reaching reliable and valid outcomes. Over the past two decades, PLS-DA has demonstrated great success in modelling high-dimensional datasets for diverse purposes, e.
View Article and Find Full Text PDFOral Health Dent Manag
June 2014
Aim: Profiles of orthodontic tooth movement biomarkers, i.e., Lactate Dehydrogenase (LDH), Aspartate Aminotransferase (AST), Tartrate-resistant Acid Phosphatase (TRAP) and Alkaline Phosphatase (ALP), using Self-ligating Brackets (SLBs) and possible relationships among their activities and total enzymes produced were determined.
View Article and Find Full Text PDFPurpose. This study is aimed to compare the effects of two different orthodontic forces on crevicular alkaline phosphatase activity, rate of tooth movement, and root resorption. Materials and Methods.
View Article and Find Full Text PDFEnviron Health Prev Med
September 2010
Objective: The health of an individual is influenced by many factors. These could include factors that are related to the economy and the environment, as well as social and biological factors. Many studies have been carried out to study the effect of these factors on health, in terms of the individual factors or combined factors.
View Article and Find Full Text PDFIntroduction: Delayed parenting and child bearing at a very young age impose various risks to development of the offspring.
Objective: This study aims to investigate the association between disparities in parental age and increased risk factor for common mental disorders in the progenies during adulthood.
Methodology: The Malaysian Mental Health Survey (MMHS) was analysed for this study.
Over the last decades, the development of the Klang Valley (Malaysia), as an urban commercial and industrial area, has elevated the risk of atmospheric pollutions. There are several significant sources of air pollutants which vary depending on the background of the location they originate from. The aim of this study is to determine the trend and status of air quality and their correlation with the meteorological factors at different air quality monitoring stations in the Klang Valley.
View Article and Find Full Text PDFThe task of identifying firearms from forensic ballistics specimens is exacting in crime investigation since the last two decades. Every firearm, regardless of its size, make and model, has its own unique 'fingerprint'. These fingerprints transfer when a firearm is fired to the fired bullet and cartridge case.
View Article and Find Full Text PDFUse of instruments or questionnaires in different cultural settings without proper validation can result in inaccurate results. Issues like reliability, validity, feasibility and acceptability should be considered in the use of an instrument. The study aims to determine the usefulness of the CIS-R Malay version in detecting common mental health problems specifically to establish the validity.
View Article and Find Full Text PDF