Purpose: Firstly, the aim of this study was to determine the maximally tolerated dose of intravitreally injected povidone-iodine (PVP-I). A second aim was to test the efficacy of PVP-I on rabbit eyes infected intravitreally with Staphylococcus epidermidis.
Methods: Phase I of the study used 16 New Zealand albino rabbits, divided into 4 groups (n=4 each).