[Distribution of HLA-DRB1 allele polymorphism in the Uyghur women with family history of cervical cancer].

Objective: To study the distribution of HLA-DRB1 allele polymorphism in Uyghur women with family history of cervical cancer, and provide theoretical evidence for detection and follow-up of high risk persons for cervical cancer by detection of HLA-DRB1 allele polymorphism.

Methods: The HLA-DRB1 13 alleles were detected in 1000 Uyghur women, all from Hotan Moyu county Karsay village by using polymerase chain reaction sequence-specific oligonucleotide (PCR-SSO) assay.

Results: The frequencies of HLA-DRB1*15 in women with family history of cervical cancer (17.

[Study on the distribution of HPV subtypes in Uighur people living in the Karsay township, Moyu county, Xinjiang].

Objective: To study the distribution of human papilloma virus (HPV) subtypes in Uyghur people from the high risk region of cervical cancer in Xinjiang.

Methods: 21 subtypes of HPV from 400 cases of men's swabs of penile and 400 cases of women's cervix swabs were detected, using flow-through hybridization and gene chip technology.

Results: (1) The positive rate of HPV among the 400 women cases was 14.