An In Vitro Study of the Effects of Methotrexate Loaded Biocomposite Beads on MG63 Osteoblast Cells.

This study aims to synthesize a new localized drug delivery system of bioglass, polyvinyl alcohol (PVA), cellulose (CNC), and sodium alginate (SA) beads as a carrier for methotrexate (MTX) drugs for the treatment of osteosarcoma. Methotrexate /Bioglass-loaded Polyvinyl/Cellulose/Sodium alginate biocomposite beads were prepared via the dropwise method with different concentrations of (65%SiO-30%CaO- 5%PO) bioglass. Samples were named B0, S0, S1, S2, and S3, respectively.

Hospital and laboratory outcomes of patients with COVID-19 who received vitamin D supplementation: a systematic review and meta-analysis of randomized controlled trials.

Coronavirus disease 2019 (COVID-19) has a wide-ranging spectrum of clinical symptoms, from asymptomatic/mild to severe. Recent research indicates that, among several factors, a low vitamin D level is a modifiable risk factor for COVID-19 patients. This study aims to evaluate the effect of vitamin D on hospital and laboratory outcomes of patients with COVID-19.

Angled ball and locator attachments for immediate loaded inclined implants used to retain maxillary overdentures: A cross over study of patient satisfaction and oral health related quality of life.

Objectives: The aim of this was to compare the influence of two different angulated abutment designs on patient satisfaction, oral health-related quality of life, and prosthetic aspects of implant-supported maxillary overdentures.

Materials And Methods: For this cross-over study, 18 patients with completely edentulous maxillary ridges opposing implant-retained mandibular overdentures received 4 implants between the maxillary sinuses using computer-guided surgery. The anterior implants were installed at canine/lateral incisor areas and inclined 15° labially.

Prosthetic complications and maintenance of different attachments used to stabilize mandibular 2-implant overdentures in patients with atrophied ridges. A 5-year randomized controlled clinical trial.

Purpose: This randomized clinical trial aimed to evaluate prosthetic complications and maintenance of different attachments used to stabilize mandibular 2-implant overdentures in patients with atrophied ridges.

Methods: Ninety edentulous patients with a maladaptive capacity of wearing conventional dentures due to mandibular ridge atrophy received 2-implants in the canine regions using computer-guided surgery. The patients were randomly assigned into three groups; (1) Bar group: overdentures were connected to the implants with bar/clip attachments, (2) Telescopic group: overdentures were connected to the implants using a resilient telescopic attachment, and (3) Stud group: overdentures were connected to the implants with resilient stud (Locator) attachments.

Milled Bar with PEEK and Metal Housings for Inclined Implants Supporting Mandibular Overdentures: 1-Year Clinical, Prosthetic, and Patient-Based Outcomes.

Purpose: This investigation aimed to evaluate clinical, prosthetic, and patient-based outcomes of a milled bar with polyether ether ketone (PEEK) and metal housings for inclined implants supporting mandibular overdentures.

Materials And Methods: Eighteen edentulous participants received four implants in the interforaminal area of the mandible (two vertically and two distally inclined), and implants were connected with milled bars. Overdentures were attached to the bars with PEEK female housing (test group).

Effect of Low-Level Laser Irradiation on Stability and Marginal Bone of Narrow Implants Retaining Overdentures in Moderately Controlled Diabetic Patients.

The researchers investigated the influence of low-level laser irradiation (LLLI) on implant stability and marginal bone of small-diameter implants retaining mandibular overdentures in patients with moderately controlled diabetes. Twenty patients (mean age = 59.32 ± 4.