Publications by authors named "Abdelouahab Beziane"

Article Synopsis
  • A new test for detecting anti-phosphatidylethanolamine autoantibodies (aPEs) could help doctors better diagnose and treat patients with antiphospholipid syndrome (APS), especially when other tests come back negative.
  • Researchers studied 1,131 patients and found that 19.5% had aPEs, which was useful for those with unexplained deep vein thrombosis (DVT).
  • They discovered a connection between having aPEs and increased production of reactive oxygen species (ROS), which points to a new way that aPEs might cause problems like blood clots.
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Objectives: Non-conventional aPL have been described in patients presenting clinical manifestations of antiphospholipid syndrome but negative for conventional markers. Among them, detection of autoantibodies against prothrombin has been proposed to improve diagnosis and management of these patients. However autoantibodies against prothrombin are heterogeneous and their use in clinical practice still remains unclear.

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A series of highly functionalized quinones was prepared by an original reaction of 2,3-bis(chloromethyl)-1,4-dimethoxyanthraquinone (6) with various nitronate anions under electron transfer reaction conditions.

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