Publications by authors named "Abdellatif Daoudi"

Holoprosencephaly (HPE) is a severe and complex congenital brain malformation caused by a defect in the midline cleavage of the prosencephalon during early embryonic development. It is the most common prosencephalic malformation in humans and is categorized into three classical forms based on the severity of this cleavage defect: alobar, semilobar, and lobar HPE. A milder interhemispheric variant, called syntelencephaly, is also considered a form of HPE.

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Article Synopsis
  • Juvenile Dermatomyositis (JDM) is an autoimmune condition in children that causes inflammation in muscles and skin, and identifying specific autoantibodies can help classify its subtypes and predict outcomes.
  • A case study describes a 5-year-old Moroccan boy with JDM who exhibited symptoms such as dysphagia, facial erythema, muscle weakness, and characteristic skin rashes, along with positive anti-SAE antibodies, a rare finding.
  • Treatment involved high-dose methylprednisolone followed by a tapering dose of oral prednisone, highlighting the need for targeted therapies based on specific antibody presence in JDM.
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Cleft palate-lateral synechiae syndrome (CPLSS) is an extremely rare congenital malformation syndrome with undetermined etiology, characterized by a cleft palate and lateral intraoral synechiae linking the free borders of the palate to the mouth floor. We report a case of a female neonate, admitted for suckling difficulties with a cleft lip and palate associated to multiple lateral intraoral synechiae. Resection of the synechiae allowed oral feeding.

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Background: Rapid and accurate diagnosis of mucopolysaccharidoses (MPS) is still a challenge due to poor access to screening and diagnostic methods and to their extensive clinical heterogeneity. The aim of this work is to perform laboratory biochemical testing for confirming the diagnosis of mucopolysaccharidosis (MPS) for the first time in Morocco.

Methods: Over a period of twelve months, 88 patients suspected of having Mucopolysaccharidosis (MPS) were referred to our laboratory.

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() is an microorganism that is widespread in the environment, which may be the source of nosocomial infections, rare in the newborn but severe, and often in the form of outbreaks. The aim of our study is to report our experience, during an outbreak of , to show the severity of this germ, with review of the literature. Our study was retrospective, including 8 newborns with nosocomial infection, collected in the neonatal intensive care unit of Mohammed VI University Medical Hospital, during the epidemic period, over a period of 2 months (July and August 2016).

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