Brain metastases of non-small cell lung cancer: prognostic factors and management.

Background: The prognosis of patients with non-small cell lung cancer (NSCLC) with brain metastasis (BM) is dark. The aim of our study was to analyze the prognostic factors after the onset of BM and to evaluate the current management of BM.

Methods: We conducted a retrospective study that included 100 patients diagnosed with primary NSCLC with BM.

Chronic arthritis revealing sarcoidosis in a patient exposed to silica.

Sarcoidosis is a systematic, granulomatous disease of unknown cause which can affect any organ in the body. Pulmonary involvement is the most common. Musculoskeletal manifestations of sarcoidosis are less common affecting 10-25% of patients and chronic arthritis occurs rarely.

Impact of malnutrition in advanced non-small cell lung cancer.

Background: Malnutrition is so commonly associated with cancer disease. Our work aims to highlight the impact of malnutrition on the survival and toxicity of chemotherapy in patients with advanced stages of non-small cell lung cancer (NSCLC).

Methods: A retrospective study including 60 patients followed for NSCLC stage IIIB and IV, between January 2007 and December 2013.

Unicentric Castleman's disease: an uncommon cause of chronic cough.

Castleman disease (CD) or angiofollicular lymph node hyperplasia is a rare lymphoproliferative disorder characterized by lymph node hyperplasia of uncertain etiology. CD is divided clinically into unicentric (localized to one region of the body) considered as a benign disease and multicentric with less favourable prognosis. We describe a case of intrathoracic unicentric CD revealed by a chronic non-productive cough in a 50-year-old non-smoker female.

Combined C-reactive protein and Neutrophil to Lymphocyte ratio use predict survival innon-small-cell lung cancer.

Background: Inflammation markers have been shown to predict prognosis during cancer including non-small cell lung cancer (NSCLC). In particular, C-reactive protein (CRP) and Neutrophil to Lymphocyte Ratio (NLR) have been investigated. The aim of our work is to study the combination of these two markers in optimizing prognostication in advanced NSCLC.

Advanced Lung Cancer Inflammation index: a prognostic score in patients with metastatic non-small cell lung cancer.

Introduction: Recent studies have identified that inflammation had a significant association with cancer development and progression.

Aim: To explore the relationship between ALI score and prognosis of metastatic non-small cell lung cancer (NSCLC).

Methods: we conducted a retrospective study of 41 patients with metastatic NSCLC diagnosed between January2010 and January2012.

Prognostic factors for second-line chemotherapy of metastatic non-small-cell lung cancer.

Background: Few studies have been conduct¬ed to determine prognostic factors of second-line chemotherapy. The aim of this study was to determine the prognostic factors for survival in patients receiving second-line treatment for advanced NSCLC.

Methods: We retrospectively reviewed the records of 71 patients with metastatic NSCLC who received second-line chemotherapy from January 2006 to January 2013.

Assessment of eating behavior after smoking cessation.

Background Weight gain is very frequent after smoking cessation and constitutes an obstacle to the decision to quit smoking. Aim To assess the impact of smoking cessation on the weight and eating behaviour. Methods This was a prospective study that included thirty four smokers.

[Extended pulmonary tuberculosis and immunocompetence: causes and consequences].

Background: Despite scientific advances, extended forms of pulmonary tuberculosis are still relevant. The aim of our study was to determine clinical features and outcome of extended pulmonary tuberculosis in immunocompetent patients.

Methods: Retrospective comparative study including 100 patients HIV negative, presenting pulmonary tuberculosis divided into 2 groups of 50 patients (group1: extended tuberculosis and group2: localized tuberculosis).

The Pollen-Food Olive-Olive Syndrome.

Background: The pollen-foods syndrome is rare and of difficult diagnosis. The aim is to report a rare case, it's the four case reported in the literature.

Case Report: A 48-year-old woman presenting with palatal itching and generalized urticaria following ingestion of olive fruit, 5 years after being diagnosed with olive pollinosis.

[Lung cancer with venous thrombo-embolism: clinical characteristics].

Background: Lung cancer is the most common malignancy diagnosed in patients with venous thrombo-embolism (VTE).

Aim: To investigate clinical, biological, radiological features and survival of lung cancer patients with VTE.

Methods: Retrospective case-control study investigating biologic, clinical course and survival of 25 patients lung cancers with VTE (Group M) and 50 lung cancers without VTE (group T).

[Palliative chemotherapy of non small lung cancer in Tunisia. Prospective study of the cost and impact on the quality of life].

Background: Bronchopulmonary cancer is actually the first cancer in the world. In Tunisia, recent statistics are alarmous. The most bronchopulmonary cancer in tunisian series are diagnosis at metastatic states.

[A rare costal tumor].

Background: Costal primary tumors are rare and dominated by malignant tumors. Hemangioma of the bone represents only 1% of the bone tumors. Costal localization accounts only for 1% of the cases and only about fifty cases have been reported in the literature.

[Pulmonary tuberculosis in smokers].

Introduction: Tobacco smoking and tuberculosis (TB) are two major public health problems, and the former may affect the morbidity and mortality rates for the latter. This study sought to compare the clinical and radiologic aspects of pulmonary TB, as well as outcome, in smokers and nonsmokers.

Methods: This retrospective case control study examined the files of 90 patients in our pulmonary department with active pulmonary TB, 45 of them smokers and 45, nonsmokers.

[The value of tumor markers in pulmonary tuberculosis].

Background: In thoracic oncology, no tumor marker has yet shown sufficient sensitivity nor specificity to be usefull for lung cancer diagnosis. However, in some cases, monitoring of tumor marker blood levels provides useful evaluation of response to specific treatment and assessment of infracfinical tumor progression.

Aim: To determine the value of umor markers in pulmonary tuberculosis.

Castleman's disease: an intrapulmonary form with intrafissural development.

Castleman's disease (CD) is an uncommon, mainly benign, lymphoproliferative disorder of unknown etiology, mostly involving the mediastinum. Parenchymal lung involvement of the disease is exceedingly rare. We describe a case of CD in a 23-year-old woman with a 4-year history of recurring dyspnea and nonproductive cough, whose chest X-ray showed an abnormal shadow of the right hilum.

Pulmonary blastomycosis: a case from Africa.

Pulmonary blastomycosis is an uncommon pathologic condition that is quite rare in Africa compared to endemic regions of Canada and the upper Midwest of the U.S. We describe a 45-year-old patient who complained of productive cough, hemoptysis, and dorsal rachiodynia.

Genetic profiling of Mycobacterium tuberculosis in Tunisia: predominance and evidence for the establishment of a few genotypes.

Typing analyses of 378 Mycobacterium tuberculosis isolates collected between the years 2001 and 2005 from three northern representative regions of Tunisia revealed a highly homogeneous population. Indeed, 84.9 % of all tuberculosis (TB) cases were attributed to the Haarlem, LAM or T families.