Acute lower limb ischemia revealing hypo granular acute promyelocytic leukemia.

Introduction: Acute promyelocytic leukemia (AML-M3), classified as acute Myeloid leukemia with PML RARA according to the 5th edition of the World Health Organization classification of haematolymphoid tumors 2022 [1], is marked by abnormal promyelocyte proliferation and is known for high risks of bleeding and thromboembolic complications. We present a case where lower limb ischemia revealed this leukemia in a child.

Case Report: An 11-year-old with minor ankle trauma developed severe lower limb ischemia, leading to the discovery of subtotal femoral artery thrombosis.

Comparative Study of Cerebrospinal Fluid Evaluation in Patients With Acute Leukemia Using the Manual Method and Sysmex XN-1000.

Background Many pathological settings can be provided by the cytological analysis of cerebrospinal fluid (CSF). In our work, we aimed to evaluate the concordance between the analysis using the reference manual method and the analysis using Sysmex XN-1000. Methods In our study, we examined 121 CSF samples.

Value of hematological parameters for predicting patients with severe coronavirus disease 2019: a real-world cohort from Morocco.

Objective: Coronavirus disease 2019 (COVID-19) is a viral disease caused by severe acute respiratory syndrome coronavirus 2. The clinical manifestations and the evolution of patients with COVID-19 are variable. In addition to respiratory involvement, COVID-19 leads to systemic involvement and can affect the hematopoietic system.

Visceral leishmaniasis associated with macrophage activation syndrome: Case report and literature review.

Background: The combination of visceral leishmaniasis (VL) and macrophage activation syndrome (MAS) makes the diagnosis difficult due to their similar clinical presentation, with a poor prognosis especially since the treatment is still poorly codified.We report the case of a 17-month-old female patient from Berkane, presenting for a 3 months history of anarchic fever with anemic syndrome made up of pallor and hemorrhagic syndrome made up of epistaxis. Physical examination revealed a temperature of 39 ° C, lower limbsedema, paleness of skin and mucous membranes, gingival petechiae, bleached hair, and hepatosplenomegaly.

Gaucher Disease: An Underdiagnosed Pathology in the Eastern Moroccan Population.

Gaucher disease (GD) is a lysosomal storage disease. It corresponds to a congenital deficit in β-glucocerebrosidase. This pathology should be considered in the presence of unexplained splenomegaly, with or without signs of haemorrhage, skeletal manifestations or hepatomegaly.