Publications by authors named "Abdelhafidh Khazri"

Bisphenol A (BPA) is a chemical compound extensively employed in plastic manufacturing, and this pollutant has been detected in diverse aquatic organisms, notably bivalves. In order to comprehend the ecological and toxicological consequences of BPA Bisphenol A in these organisms, it is essential to examine the physiological and biochemical effects and identify areas where our understanding is lacking. This knowledge is crucial for determining the environn ental threat posed by bisphenol A and assisting decision-makers in establishing the appropriate priorities.

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Environmental research plays a crucial role in formulating novel approaches to pollution management and preservation of biodiversity. This study aims to assess the potential harm of pharmaceutical triclosan (TCS) to non-target aquatic organism, the mussel Mytilus galloprovincialis. Furthermore, our study investigates the potential effectiveness of TiO and ZnO nanomaterials (TiO NPs and ZnO NPs) in degrading TCS.

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Background: While previous studies have provided insights into the effects of zinc oxide (ZnO) and titanium dioxide (TiO) nanoparticles (NPs) on aquatic organisms, there is still a substantial amount of information lacking about the possible effects of their doped counterparts. The goal of the current work was to address this gap by examining Mytilus galloprovincialis reaction to exposure to doped and undoped nanoparticles.

Methods: Two concentrations (50 or 100 µg/L) of undoped ZnO and TiO NPs, as well as their gold (Au) doped counterparts, were applied on mussels for 14 days, and the effects on biomarkers activities in digestive glands and gills were assessed by spectrophotometry.

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Inevitably, high concentrations of iron, the most widely produced ore globally, can be found in aquatic environments. To assess the toxicity of iron on aquatic organisms, specimens were subjected to microparticles derived from two types of iron ore (hematite and magnetite) at four different concentrations (0.5, 1, 1.

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Article Synopsis
  • The study investigates the effects of nano-zinc oxide (nZnO), a common pollutant, on freshwater mussels, an important indicator species in ecotoxicology, by exposing them to different concentrations of nZnO and zinc ions for seven days.
  • Results revealed significant changes in oxidative stress markers in the mussels, such as increased catalase (CAT) and acetylcholinesterase (AChE) activity, along with elevated malondialdehyde (MDA) levels, indicating oxidative stress due to nZnO exposure.
  • The study sheds light on the environmental toxicity of nanoparticles, specifically how nZnO affects mussel behavior and filtration rates, and provides new insights into the interaction between nanoparticles and b
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This study aims to evaluate the toxicity of ZnS nanoparticles (ZnS NP50 = 50 µg/L and ZnS NP100 = 100 µg/L) and diethyl (3-cyano-1-hydroxy-2-methyl-1-phenylpropyl)phosphonate or P (P50 = 50 µg/L and P100 = 100 µg/L) in the clams using chemical and biochemical approaches. The results demonstrated that clams accumulate ZnS NPs and other metallic elements following exposure. Moreover, ZnS NPs and P separately lead to ROS overproduction, while a mixture of both contaminants has no effect.

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The aim of this work was to study the ecotoxicological effects of an endocrine disruptor triclosan on the clam . The bivalves were exposed to three concentrations of this biocide (C1 = 100 ng/L, C2 = 200 ng/L and C3 = 500 ng/L) for three and seven days. The impact was assessed at the gills and digestive glands, through activities of an antioxidant defense biomarker (Gluthatione -Transferase, GST), a damage biomarker (Malondialdehyde, MDA), and a neurotoxicity biomarker (Acetylcholinesterase, AChE).

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Diuron herbicide is widely used for weeds control in many kinds of cultivations. It reaches the waterbodies through various fate routes and can adversely threaten non-target organism. The current study was carried out to evaluate the antioxidant activity of Spirulina as feed additive against the toxicity of Diuron concentrations (40 and 80 µg/L) on the edible mollusk during seven days of exposure.

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Organophosphorus derivatives are widely used in human health care and have been detected in aquatic ecosystems. These compounds may pose significant risks to non-target exposed organisms and only limited studies are available on bioconcentration and the effects of organophosphorus derivatives on marine organisms. The aim of this work was to evaluate the possible toxic effects of two concentrations (20 and 40 μg/L) of γ-oximo- and γ-amino-phosphonates and phosphine oxides in mediterranean clams Ruditapes decussatus exposed for 14 days using different biomarkers and the changes of filtration and respiration rate.

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Context: The Au-TiONPs have a wide range of applications and can easily enter the cells. Due to their properties, they can cause toxicity.

Objective: It was aimed to test the toxic effects of Au-TiO NPs in the brain, heart, kidney and liver of rats in this work.

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Glyphosate is a toxic environmental pollutant that has the ability to induce biochemical and physiological alterations in living organisms. Several studies have focused on the research of protective techniques against the stress induced by this contaminant. In this context, we studied the protective effect of against the disturbances induced by glyphosate.

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Cypermethrin (Cyp) is a kind of pyrethroids compound that is broadly used against different species of insects and pests. Cyp can also elicit a range of neurotoxic, immunotoxic, genotoxic and reproductive toxic effects on various experimental organisms. The aim of this study was to evaluate the protective effects of Hibiscus sabdariffa against the toxicity damage induced by Cyp exposure.

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A new synthetisis method of Cu-doped ZnO nanoparticles is presented in this work, this novel approach allow one to produce Zinc oxide nanocristal owing to a modified Polyol process that makes use of triethyleneglycol (TREG) as a solvent. The structure and morphology of the nanoparticles were characterized by high-resolution transmission electron microscopy (HRTEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), N adsorption study, UV-Vis diffuse reflectance spectroscopy, inductively coupled plasma optical emission spectroscopy and Raman spectroscopy. The lightly doped ZnCuO photocatalysts consisted in a novel nanorods structure of ZnCuO nanoparticles.

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Nanoparticle decoration with noble metal represents a promising alternative to improve their photocatalytic and photovoltaic properties. However, toxicity can be influenced by such modification, as the bioavailability of these substances may be influenced. To understand how decoration influences the NP impacts in marine ecosystems, we exposed suspension-feeding clams, Ruditapes decussatus, to two photocatalyst nanocomposites, TiO NPs and AuTiO NPs, over 2 concentrations, 50 μg Land 100 μg L, in a laboratory experiment.

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The increased use of gold nanoparticles (AuNPs) in several applications has led to a rise in concerns about their potential toxicity to aquatic organisms. In addition, toxicity of nanoparticles to aquatic organisms is related to their physical and chemical properties. In the present study, we synthesize two forms of gold octahedra nanoparticles (Au_ and Au_) in 1.

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Context: Nanoparticles may cause adverse environmental effects but there is limited information on their interactions with marine organisms.

Objective: Our aim was to examine the effects of triangular gold nanoparticles (Tr-Au NPs) on the clam, Ruditapes decussatus.

Materials And Methods: Clams were exposed to Tr-Au1 = 5 µg/L and Tr-Au2 = 10 µg/L for 2 and 7 days.

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Context: Cypermethrin (CYP) is a synthetic pyrethroid insecticide used worldwide in agriculture, home pest control. The toxicity of CYP is well studied in many organisms.

Objective: The aim of present study was to investigate the protective effect of Zizyphus lotus (Zizyp) fruit against neurotoxicity and oxidative stress induced by CYP in mice.

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1. Laboratory experiments were carried out to assess uptake and metabolism of the epilepsy drug, carbamazepine and its consequent biological responses in marine clam (Ruditapes decussatus) a model non-target organism in ecotoxicology. 2.

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The synthesis of hybrid nanomaterials has greatly increased in recent years due to their special physical and chemical properties. However, information regarding the environmental toxicity associated with these chemicals is limited, in particular in the aquatic environment. In the present study, an experiment was performed in which the marine bivalve (Ruditapes decussatus) was exposed for 14days to 2 concentrations of zinc oxide-decorated Au nanoparticles (Au-ZnONPs: Au-ZnONP50=50μg/L; Au-ZnONP100=100μg/L).

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A mesocosm experiment was conducted to evaluate the effects of Irgarol on nematode diversity, composition and trophic structure. Sediment samples were experimentally contaminated using four increasing Irgarol concentrations [I1 (11.5 ng g(-1)), I2 (35 ng g(-1)), I3 (105 ng g(-1)) and I4 (315 ng g(-1))] and compared to non-contaminated sediments (controls).

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Synthetic pyrethroids are a family of chiral pesticides with a large number of stereoisomers. Cypermethrin (CYP) is used in a variety of agricultural crops, but also has public health and veterinary uses. In this work, the freshwater mussel (Unio gibbus) was chosen to evaluate the stereoselectivity of CYP through the use of gas chromatography with mass-spectrometry.

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Lithium (Li) has raised scientific concern because it represents a serious problem threatening human health. This study aimed firstly at analyzing and potentially quantifying the impact of Li and grape seed and skin extract (GSSE) separately and, secondly, describing the possible neuroprotective activity of GSSE against Li toxicity. To this end, rats were exposed for 30 days to different Li concentrations (0, 2, and 100 mg/kg bw), to GSSE (4000 mg/kg bw), and to binary mixture of Li and GSSE.

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The biocide Irgarol 1051 has been reported to have negative effects on a large number of living components including non-target organisms, but information on its impact on the marine meiofauna and benthic prokaryotes is completely lacking. Here, we report the results of long-term experimental studies in which we determined the effects of increasing Irgarol concentrations (from 11.5 to 315 ng g(-1) sediment dry weight) on meiofauna and benthic prokaryotes.

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This study aimed at analyzing the impact of a toxic polyaromatic hydrocarbon (PAH), anthracene (ANT), on Ruditapes decussatus collected from a Tunisian coastal lagoon (Bizerte Lagoon). Filtration rates, several antioxidant enzymes--superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), and glutathione transferase (GST)--as well as indices of protein oxidation status were determined in various tissues of this bivalve. Specimens were exposed to 100 μg/L of ANT for 2 days.

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Cypermethrin is a synthetic pyrethroid insecticide used worldwide in agriculture, home pest control, food stuff protection and disease vector control. We investigate the potential of cypermethrin to induce oxidative stress and enzyme activities within the gills of freshwater mussel Unio gibbus. This study was carried out under laboratory conditions using two nominal cypermethrin concentrations C1 (100µg/L) and C2 (150µg/L) during 96h.

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