The relationship between telomere length and clinicopathologic characteristics in colorectal cancers among Tunisian patients.

Alterations in telomere dynamics have emerged as having a causative role in carcinogenesis. Both the telomere attrition contribute to tumor initiation via increasing chromosomal instability and that the telomere elongation induces cell immortalization and leads to tumor progression. The objectives of this study are to investigate the dynamics of telomere length in colorectal cancer (CRC) and the clinicopathological parameters implicated.

[Primary necrosis of the ligamentum teres hepatis].

Aim: report a new case of primary necrosis of the ligamentum teres hepatis and discuss preoperative diagnosis strategy and therapeutic options.

Observation: This is a patient of 76 years, hypertensive, who was admitted for an acute abdomen. The diagnosis of acute pancreatitis was referred to the poor clinical examination and amylase to six times normal.

Spontaneous fistulization of hepatic hydatid cyst into the duodenum: an exceptional complication.

Hydatid disease is a worldwide zoonosis and is localized in the liver in most cases. Its complications are numerous and include those related to the compression of adjacent viscera, infection of the cyst's contents or perforation of the cyst. Spontaneous rupture of the hepatic hydatid cyst into the duodenum is an extremely rare complication.

Jejunal GIST causing acute massive gastrointestinal bleeding: role of multidetector row helical CT in the preoperative diagnosis and management.

In this report, we describe a 34-year-old man with a jejunal gastrointestinal stromal tumour (GIST) accompanied by an unusual severe haemorrhage. Because oesophagogastroduodenoscopy proved inconclusive in determining the source of the bleeding and also because of gradually dropping haemoglobin levels and persistence of the melena not allowing colonic preparation, colonoscopy was cancelled and a mesenteric angio-computed tomography (angio-CT) was deemed necessary. The results of this analysis showed a 5-cm heterogeneous mass located in the jejunal loop surrounded by abnormal arterial structures.

Unusual presentation of a colonic sarcoidosis.

Sarcoidosis is a multisystemic disorder of unknown cause that affects almost every tissue in the body. Colon is an extremely rare location of this disease. Clinical presentation, endoscopic appearances, and radiologic findings are not specific and may mimic much other affection.

A new case of spontaneous regression of inflammatory hepatic pseudotumor.

Introduction. Inflammatory pseudo-tumors (IPT) of the liver are rare and difficult to diagnose, because mimicking malignant tumors. Aim.

A rare cause of lower gastrointestinal bleeding.

Background: Leiomyoma of the colon are rare benign smooth muscle tumours.

Aim: Report a new case of colic leiomyoma revealed by gastrointestinal bleeding.

Case: A 71-year-old man, diabetic, consulted the emergencies for acute per-rectal bleeding.

Relationship between subcutaneous adipose tissue expression of leptin and obesity in Tunisian patients.

Background: The incidence of obesity has dramatically increased in overall the world. It is a consequence of imbalance between energy intake and energy expenditure. Leptin is a fat derived adipokine that has emerged over the past decade as a key hormone in the regulation of food intake and energy expenditure.

Primary anorectal melanoma: a case report.

Background: Anorectal melanoma is a rare but highly lethal malignancy. Clinical symptoms are non-specific and treatment is still debated.

Aim: The aim of this study was to report a case concerning diagnostic and management of Anorectal melanoma.

[Descending necrotizing mediastinitis of odontogenic origin].

Background: Descending necrotizing mediastinitis (DNM) following an oropharyngeal infection is a rare disease with a rapid course and a mortality rate of up to 40%. The aim of this study, is to outline the diagnosis and the appropriate treatment of DNM.

Methods: A retrospective study (1986-2007) of patients with DNM was made.

Stromal tumor of the ampulla of vater: report of a case and systematic review of reported cases.

Background: Gastrointestinal stromal tumours are a large category of primary no epithelial neoplasms of the digestive tract. The localization of stromal tumours in the ampulla of Vater (STAV) is very rare.

Aim: The aim of this study was to describe clinical, endoscopic and therapeutic particularities of STAV.