Publications by authors named "Abdel-Sattar Arafa"

Article Synopsis
  • Several genotypes of the highly pathogenic avian influenza (HPAI) virus H5N8 are circulating among domestic birds in Egypt, with quail playing a key role in its replication and potential adaptation to humans.
  • This study involves genetic characterization of H5N8 isolated from a commercial quail farm, revealing high genetic similarity to other circulating strains in Egypt and features indicating increased virulence in mammals.
  • Findings highlight the absence of antiviral resistance markers and underscore the need for continuous surveillance and genomic analysis of avian influenza in diverse bird species in Egypt for effective control measures.
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Controlling avian influenza viruses (AIVs) is mainly based on culling of the infected bird flocks or via the implementation of inactivated vaccines in countries where AIVs are considered to be endemic. Over the last decade, several avian influenza virus subtypes, including highly pathogenic avian influenza (HPAI) H5N1 clade 2.2.

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Article Synopsis
  • - Highly pathogenic avian influenza (HPAI) viruses H5N1 and H5N8 have been major causes of bird outbreaks globally, with significant implications for public health.
  • - A study analyzed outbreak data from 2015-2020, revealing that H5N8 was more prevalent (61%) than H5N1 (39%), particularly in backyard settings in Egypt.
  • - Findings suggest a competitive relationship between H5N1 and H5N8, indicating potential replacement dynamics, but further research is needed to understand the mechanisms behind this and improve disease control strategies.
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Highly pathogenic avian influenza (HPAI) viruses of subtype H5N8 continue to circulate, causing huge economic losses and serious impact on poultry production worldwide. Recently, HPAIV H5N8 has been spreading rapidly, and a large number of HPAI H5N8 outbreaks have been reported in Eurasia 2020-2021. In this study, we conducted an epidemiological survey of HPAI H5N8 virus at different geographical locations in Egypt from 2017 to 2019.

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Avian influenza H9N2 (AIV-H9N2) and Infectious bronchitis (IB) viruses are the most commonly isolated viruses from poultry flocks suffering from respiratory signs with mortalities. The outcome of co-infection with both viruses hasn't been yet well understood. In this study, eighty 1-day-old specific pathogen free chicks were divided into four distinct groups.

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