Today, high-energy applications are devoted to boosting the storage performance of asymmetric supercapacitors. Importantly, boosting the storage performance of the negative electrodes is a crucial topic. FeO-based active materials display a promising theoretical storage performance as a negative electrode.
View Article and Find Full Text PDFBackground: Many of the pediatric health care workers (HCWs) suffered from sleep disturbance, anxiety, and potential stress disorder during the COVID-19 pandemic. Work-related stress is a potential cause of concern in HCWs and is associated with decreased job satisfaction, anxiety, depression, medical errors, and near misses. This study aims to investigate the various psychological consequences on medical personnel working in the neonatal intensive care unit (NICU) in the context of the COVID-19 pandemic.
View Article and Find Full Text PDFCOVID-19 is a pandemic disease caused by SARS-CoV-2, which is an RNA virus similar to the hepatitis C virus (HCV) in the replication process. Sofosbuvir/ledipasvir is an approved drug to treat HCV infection. This study investigates the efficacy of Sofosbuvir/ledipasvir as a treatment for patients with moderate COVID-19 infection.
View Article and Find Full Text PDFObjective: Maternal malnutrition with disturbed lipid metabolism during pregnancy may affect the fetal lipid profile. We aimed to detect the relation between maternal and neonatal serum lipid profile, as well as to detect the serum lipid profile difference between small for gestational age (SGA) infants and appropriate for gestational age (AGA) infants to disclose the impact of maternal malnutrition on birth weight.
Study Design: A cross-sectional study was conducted on 150 pregnant women coming to the labor room.
For its role in the mediation of growth hormone (GH) galactopoietic effect, growth hormone receptor () was considered a functional candidate gene for milk performance in cattle. However, its genetic variation and potential effect have not been investigated in Egyptian buffaloes. This study aimed to screen for polymorphisms and study their associations with milk traits in Egyptian buffaloes.
View Article and Find Full Text PDFBackground: Annexin A1 (ANXA1) is an important anti-inflammatory mediator that may play a significant role in bronchial asthma. MiR-196a2 can target ANXA1 and therefore may play a role in the pathogenesis of asthma.
Aim Of Study: This is the first study which aimed to evaluate the expression of miR-196a2 in the serum of asthmatic children and correlate its expression with ANXA1 serum level and asthma severity.
J Pediatr Endocrinol Metab
October 2019
Background Recent emerging evidence supports the role of miR-196a2 in various human diseases. However, its role in type 1 diabetes mellitus (T1DM) is still underestimated. We aimed, for the first time, to investigate the expression of miR-196a2 in T1DM and the association of miR-196a2 (rs11614913) polymorphism with susceptibility of T1DM in a sample of patients from Cairo, Egypt.
View Article and Find Full Text PDFThe aim was to evaluate the effect of bee pollen (BP) on performance, blood parameters, and metabolic hormones in New Zealand White (NZW) and Rex (RX) rabbits. A total of 60 six-week-old rabbits were allotted into a completely randomized design in a 2 × 3 factorial arrangement (two breeds and three levels of BP: 0, 250, and 350 mg/kg body weight). The effects of breed × BP supplementation level were non-significant for all growth performance and carcass traits, as well as the concentrations of metabolic hormones in the plasma.
View Article and Find Full Text PDFIntroduction: Adiponectin, leptin and resistin are adipokines that play important roles in the regulation of lipid and carbohydrate metabolism in type 2 diabetes (T2DM). However, their influence in type 1 diabetes mellitus is still unknown. The aim of this study was to measure serum adiponectin, leptin and resistin levels and to investigate their relationships with vitamin D and other clinical and laboratory parameters in patients with type 1 diabetes.
View Article and Find Full Text PDFA trial was conducted to explore the effect of feeding graded concentrations of green tea extract (GTE; 125, 250, 500, 1000 and 2000 mg/kg) on the growth performance, serum lipid profile, liver glutathione-reduced, thigh muscle malondialdehyde and humoral immune response against Newcastle disease virus vaccines of broiler chickens from hatching to 42 d of age. The results of broilers fed on GTE were contrasted to those fed on butylated hydroxytoluene (BHT; 125 mg/kg) or unsupplemented controls. The obtained results revealed no significant difference among treatments in the measured growth performance parameters (body weight, average daily gain, average daily feed intake and feed conversion ratio), per cent liveability and serum lipid profile (total lipid, total cholesterol, high-density, low-density and very low-density lipoprotein cholesterols).
View Article and Find Full Text PDFChicken growth hormone secretagogue receptor (GHSR) is a receptor for ghrelin (GHRL), a peptide hormone produced by chicken proventriculus, which stimulates growth hormone (GH) release and food intake. The purpose of this study was to search for single nucleotide polymorphisms (SNPs) in exon 2 of GHSR gene and to analyze their effect on the appetite, growth traits and expression levels of GHSR, GHRL, and GH genes as well as serum levels of GH and GHRL in Mandara chicken. Two adjacent SNPs, A239G and G244A, were detected in exon 2 of GHSR gene.
View Article and Find Full Text PDFBackground: Vitamin D3 (VD3 ) levels have been recently found to be responsible for a number of immunological, anti-inflammatory and anti-infectious roles. Some studies reported that some forms of allergic fungal rhinosinusitis (AFRS), occurs more commonly in patients who are more susceptible to VD3 deficiency. The aim of this work was to measure VD3 levels in patients with AFRS and chronic rhinosinusitis (CRS).
View Article and Find Full Text PDFHuman body energy storage operates as a stock-and-flow system with inflow (food intake) and outflow (energy expenditure). In spite of the ubiquity of stock-and-flow structures, evidence suggests that human beings fail to understand stock accumulation and rates of change, a difficulty called the stock-flow failure. This study examines the influence of health care training and cultural background in overcoming stock-flow failure.
View Article and Find Full Text PDFIntroduction: Acute myeloid leukemia (AML) is a highly heterogeneous disease, with biologically and prognostically different subtypes.
Aim: To study the impact of p53, p21, and mdm2 gene polymorphisms on the clinical outcome in adult AML patients treated at the National Cancer Institute (NCI) - Cairo University.
Methods: Forty-eight adult AML patients presented to the Medical Oncology Department, NCI, from April 2010 till November 2011.
Background: Wilms' tumor (WT1) gene overexpression has been reported in the majority of acute myeloid leukemia (AML) patients at diagnosis and has been evaluated as prognostic and minimal residual disease (MRD) marker.
Patients And Methods: WT1 overexpression was evaluated in 68 adult AML patients at diagnosis and at the end of induction using quantitative real-time polymerase chain reaction (PCR).
Results: No significant associations were encountered between WT1 overexpression at diagnosis and other prognostic factors.
J Egypt Natl Canc Inst
December 2009
Background: Following gene expression profiling which compared the two well established prognostic markers in CLL, ZAP-70 and CD38 with unmutated and mutated IgVH, ZAP-70 has emerged as the most promising surrogate marker for the IgVH mutation status. CD38 expression has also been suggested as a surrogate marker for the IgVH mutation status.
Aim: We aimed to investigate the impact of ZAP-70 and CD38 expressions as well as their combined expressions on the treatment outcome and survival of our CLL patients.
When companies put seasoned managers in charge of important projects, they don't expect missed deadlines, budget overruns, and rampant defects. However, that's what researchers found when they tested hundreds of experienced project managers with computer games that simulated software development projects. The study, conducted by two professors from Insead and one from Naval Postgraduate School, strongly suggests that veterans in complex environments suffer a breakdown in the learning process.
View Article and Find Full Text PDFBackground And Purpose: Heterogeneity in patient' s response to chemotherapy is consistently observed across populations. Pharmacogenomics, the study of inherited differences in drug disposition and effects, is emerging as a tool to predict efficacy and toxicity of drugs. Glutathione S-transferases (GST) are involved in the metabolism and detoxification of environmental carcinogens and some classes of chemotherapeutics.
View Article and Find Full Text PDFObjective: The aim of this study was to compare the standard prognostic factors of Hodgkin's lymphoma (HL) in relation to response to first line chemotherapy, disease free survival (DFS) and overall survival (OS).
Patients And Methods: The study was performed on a group of 100 adult patients diagnosed as HL and who were treated and followed-up in the years 1999 to 2001, in the Medical Oncology Department at National Cancer Institute (NCI), Cairo. The first line chemotherapy was COPP in 40%, ABVD in 35% and COPP/ABV hybrid in 25%.
Med Sci Sports Exerc
March 2003
Purpose: Demonstrate the utility of System Dynamics computer modeling to study and gain insight into the impacts of physical activity and diet on weight gain and loss.
Methods: A holistic System Dynamics computer model is presented that integrates the processes of human metabolism, hormonal regulation, body composition, nutrition, and physical activity. These processes are not independent of one another, and the model captures the complex interdependencies between them in the regulation of body weight and energy metabolism.
J Egypt Public Health Assoc
February 2007
A study was carried out on 180 sera collected from inhabitants of a seepage flooded village (Begiram) in a Nile Delta governorate in Egypt. The aim of the study was to monitor the prevalence of certain arboviruses; some of them are known to be endemic in Egypt. Sera were screened by ELISA except for the HTN by IF, and the results indicated that WN and SFS exhibited the highest prevalence 45.
View Article and Find Full Text PDFInt J Clin Pharmacol Res
December 1993
The in-vitro interaction between clindamycin and trimethoprim was tested on 10 staphylococcal clinical isolates by the checkerboard technique and by the time-kill curve. Indifference was demonstrated against seven of these strains and antagonism against three. The clindamycin/trimethoprim combination is of no value if the purpose of the combination is to obtain synergy against staphylococci.
View Article and Find Full Text PDFIn view of high mortality, variable clinical presentation, and late results of bacterial culture, early diagnosis of SBP and treatment are based on indirect parameters of infection. Forty-two patients with ascites and liver cirrhosis were studied. Ascitic fluid (AF) was examined for total protein content, pH, lactate dehydrogenase, amylase, absolute polymorphonuclear cell count (PMN) and for presence of bacteria by examining a fresh smear of the deposit and culture of the fluid under aerobic and anaerobic conditions.
View Article and Find Full Text PDFJ Egypt Public Health Assoc
June 1977