Publications by authors named "Abdel Aziz A Diab"
Background: Type 2 diabetes is one of the most prevalent chronic diseases worldwide, significantly impacting patients' quality of life. Current treatment options like metformin (MET) effectively counteract hyperglycemia but fail to alleviate diabetes-associated complications such as retinopathy, neuropathy, nephropathy, hepatopathy, and cardiovascular diseases.
Aim: To propose the supplementation of cholecalciferol (CHO) and taurine (TAU) to enhance MET efficacy in controlling diabetes while minimizing the risk of associated complications.
Article Synopsis
- Preeclampsia (PE) is a serious pregnancy condition linked to high maternal and fetal health risks, possibly caused by imbalances in key biological factors.
- This study aimed to explore how levels of serum apelin, an important protein, relate to inflammation, oxidative stress, and blood vessel growth in a rat model of PE and whether administering apelin could offer protection against the condition.
- Researchers used different groups of pregnant rats, with some receiving an agent to induce PE and others receiving apelin; they measured various health indicators, including blood pressure and protein levels in urine, to assess the condition's impact.
Pre-eclampsia (PE) accompanying acute liver and kidney injury has remained a master cause of both fetal and maternal mortality and morbidity. Vasoactive mediators, oxidative stress and inflammatory imbalanceshave an important role in PE pathogenesis. Apelin is an adipokine that improves endothelial dysfunction; has anti-inflammatory and antioxidant effects; moreover, its level reduced during PE.
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