Phenotypic Characterization of Human Monocytes following Macronutrient Intake in Healthy Humans.

Background: Three subsets of human monocytes in circulation have been identified and their characterization is still ill-defined. Although glucose and lipid intakes have been demonstrated to exert pro-inflammatory effects on mononuclear cells (MNCs) of healthy subjects, characterization of monocytes phenotypes following macronutrient (glucose, protein, and lipid) intake in humans remains to be determined.

Methods: Thirty-six healthy, normal weight volunteers were recruited in the study.