The efficacy of new neuronal growth factor in the healing of the sciatic nerves in rabbits.

Background And Objective: Regeneration of nervous tissue is unpredictable and an ideal growth factor to influence the healing of the injured nerves is not available. A recent study in rats had shown that a new neuronal growth factor (NNGF) was effective in the early healing of the sciatic nerves. The aim of this experimental study is to test the efficacy of NNGF in the healing of iatrogenic division of the sciatic nerves in a larger animal (rabbits).

Quality of life post total knee arthroplasty: Saudi Arabian experience.

Background And Objective: Osteoarthritis of knee is quite common in Saudi Arabian population. Total knee arthroplasty (TKA) was reluctantly accepted in Saudi Arabia about 2 decades ago but there are few small number reports on quality of life (QOL) postsurgery. The objective of this study was to investigate the QOL and overall satisfaction postTKA.

Osteoporosis: Is the prevalence increasing in Saudi Arabia.

Background And Objective: The objective of this analysis is to report from a teaching hospital in eastern Saudi Arabia hospital based prevalence of osteopenia and osteoporosis.

Methods: This is a retrospective study of all patients who underwent dual-energy X-ray absorptiometry (DXA) scan between January 1, and December 31, 2018, at King Fahd Hospital of the University at Alkhobar, Saudi Arabia. Demographic data of patients, which included age, sex, diabetes mellitus status based on fasting blood sugar, hemoglobin A1C, Vitamin D level, parathormone level, and T score of the neck of femur and lumbar spine was extracted from the Quadrumed patient care system.

The clinical and radiological effectiveness of autologous bone marrow derived osteoblasts (ABMDO) in the management of avascular necrosis of femoral head (ANFH) in sickle cell disease (SCD).

Purpose: Avascular necrosis of the femoral head is a common issue faced by orthopaedic surgeons that ranges between 10 and 18%, but in patients with SCD, the incidence reaches 30%. There is no definite treatment except joint arthroplasty. Regenerative medicine is an option to cure or delay joint arthroplasty.

COVID-19 Pandemic Impact on Orthopaedic Trauma Practice: A Global Perspective.

Background And Objective: We conducted a systematic review to evaluate the global impact on orthopaedic trauma admissions during the COVID-19 crisis and compare it to that in Saudi Arabia.

Methods: We conducted an extensive search of the PubMed and the Cochrane Central Register of Clinical Trials databases for articles published on orthopaedic trauma during the pandemic. We used the terms "orthopaedic trauma", "coronavirus", "covid-19", and "Sars-cov-2" for the search.

Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial.

Results: There were a total of 60 patients who were followed up. Three patients in Group II were removed from the analysis as they underwent total knee arthroplasty (TKA). A notably significant improvement was noticed in the ABMDC group on all scores of VAS and MKSSSF with < 0.

Spinal cord injury regeneration using autologous bone marrow-derived neurocytes and rat embryonic stem cells: A comparative study in rats.

Background: Spinal cord injury (SCI) is an important cause of traumatic paralysis and is mainly due to motor vehicle accidents. However, there is no definite treatment for spinal cord damage.

Aim: To assess the outcome of rat embryonic stem cells (rESC) and autologous bone marrow-derived neurocytes (ABMDN) treatment in iatrogenic SCI created in rats, and to compare the efficacy of the two different cell types.

Low Bone Mass Secondary to Antipsychotic Medications.

Background And Objective: Antipsychotic medications are known to cause low bone mass. The objective of this study was to assess the prevalence of osteopenia and osteoporosis secondary to patients taking antipsychotic medications.

Patients And Methods: This prospective study included 175 patients taking antipsychotic medications and attending the psychiatric clinics at the King Fahd Hospital of the University, Al-Khobar, Saudi Arabia.

Blood utilization in orthopedic and trauma practice.

Objectives: Very little is known about blood utilization in orthopedic and trauma surgery and there is no definite policy in this regard. Our objective is to perform an audit on our practice of blood utilization in the orthopedic department.

Methods: We have retrospectively analyzed the data of patients who were admitted between January 2011 and December 2012 to the orthopedic male, female and pediatric wards for which blood products were requested.

Tibial cortical thickness: A dependable tool for assessing osteoporosis in the absence of dual energy X-ray absorptiopmetry.

Background And Objective: Bone mineral density measurements with absorptiometry dual-energy X-ray absorptiometry (DXA) is the gold standard for diagnosing low bone mass and risk for fragility fractures. DXA is not available at every center, and physicians require an alternative method of diagnosis before referring patients. We conducted this study to assess and compare total cortical thickness (TCT) and its relation to the T score by DXA and its correlation-ship in the diagnosis of osteoporosis.

The Quality of Life (QOL) after Total Knee Arthroplasties among Saudi Arabians: A Pilot Study.

Background And Objective: Total knee arthroplasty (TKA) is commonly performed in Saudi Arabia but there is very limited published data on outcome and quality of life (QOL) post Knee arthroplasty. To assess the QOL post TKA we performed this retrospective study.

Methods: Total Knee arthroplasty was started in mid- 2000's at the university hospital.

Prevalence of surgical site infection in orthopedic surgery: a 5-year analysis.

Surgical site infection (SSI) is disastrous in orthopedic practice as it is difficult to rid the bone and joint of the infection. This study was aimed to assess the prevalence of SSI in orthopedic practice and to identify risk factors associated with surgical site infections. All patients admitted to the orthopedic male and female wards between January 2006 and December 2011 were included in the study group.

Identification of adverse events in orthopaedic practice: a step towards quality care.

Adverse Events (AE's) are unintended injuries or complications resulting in death, disability or prolonged hospital stay, that arise from deficiency in the health care management. The objective of this retrospective study is to assess the incidence of AE's, its impact on patients in terms of morbidity and mortality. All orthopaedic patients admitted to the male orthopaedic ward between 1st August 2010 to 31st July 2011, were included.

Medication burden of Saudi Arabian women receiving antiresorptive therapy.

Background And Purpose: Osteoporosis is common in the Saudi Arabian population, and its successful treatment requires full compliance. Patients who require antiresorptive therapy, such as oral bisphosphonates, may suffer from other diseases requiring medications, which increases the medication burden and ends up in drug noncompliance on the part of patients, making them vulnerable to osteoporosis-related fractures. We decided to undertake this study to analyze the concomitant medications that osteoporotic patients are receiving at King Fahd Hospital of the University, Al Khobar.

Genetic markers for idiopathic scoliosis on chromosome 19p 13.3 among Saudi Arabian girls: A pilot study.

Background And Objective: Genetic locus linked to chromosome 19p for Adolescent idiopathic scoliosis (AIS) has been described. This study was carried out with the aim to find any significant linkage or association between three microsatellite markers (D19S216, D19S894, and DS1034) of chromosome 19p13.3 in Saudi Arabian girls with AIS.

Are we missing osteoporosis-related vertebral fractures in men?

Study Design: Retrospective study.

Purpose: To assess the prevalence of osteoporosis related spinal fractures among Saudi Arabian males.

Overview Of Literature: Vertebral fractures are the most common complication of osteoporosis and is the first sign in both sexes and only 25 to 30% of radiographically observed vertebral deformities are recognized.

Medication administration errors in Eastern Saudi Arabia.

Objective: To assess the prevalence and characteristics of medication errors (ME) in patients admitted to King Fahd University Hospital, Alkhobar, Kingdom of Saudi Arabia.

Methods: Medication errors are documented by the nurses and physicians standard reporting forms (Hospital Based Incident Report). The study was carried out in King Fahd University Hospital, Alkhobar, Kingdom of Saudi Arabia and all the incident reports were collected during the period from January 2008 to December 2009.

Genetic markers for idiopathic scoliosis in arab population: a pilot study.

Study Design: Cross-sectional screening.

Purpose: This study was conducted to determine if there is any association of the three microsatellite markers on chromosome 19p 13.3 in unrelated Saudi Arabian girls who were suffering with adolescent idiopathic scoliosis (AIS) and their healthy siblings.

Bacterial flora on cell phones of health care providers in a teaching institution.

We conducted a cross-sectional study involving culture of cell phones of 288 health care providers (HCP) during a 6-month period. One hundred nine (43.6%) HCP carried infective organisms on their cell phones.