Publications by authors named "Abdallah E Shelil"
Article Synopsis
- - Retinoblastoma (RB) is the most common eye cancer in children, primarily caused by mutations in the RB1 gene, following the "two-hit" theory of genetics.
- - This study aimed to compare two genetic testing methods, MLPA and FISH, to detect RB1 copy number variations in Egyptian patients with RB.
- - The findings indicated that MLPA is a faster and more effective method for screening RB1 CNVs and assessing gene methylation, making it preferable over FISH for initial testing.
Objectives: We aimed to study the clinical state and prognosis of patients with unilateral retinoblastoma who were being treated at a paediatric comprehensive cancer centre in a limited-resource country, to assess the different phases of treatment and the success of different, more complex real-life models.
Subjects: In this retrospective study, we created a snapshot of our retinoblastoma database for the period between 2007 and 2015. Patients whose data were included in the study were followed up until 2016.
Purpose: To detect the need of adjusting the apical total dose according to the new NIST calibration measurement introduced by BEBIG Isotopen und Medizintechnik GmbH for the treatment of choroidal melanoma. As the total radiation dose should not be individualized depending on errors pf previous calibration but can be applicable if based on a radiosensitivity test that was able to predict the final response of tumor to radiation for each particular patient.
Patients And Methods: Twenty patients with choroidal melanomas were treated between November 2002 and July 2004 at "Suzanne Mubarak Eye Tumor Centre", National Eye centre Rod-EL Farag, Cairo, Egypt.