Obesity leads to increased oxidative stress and inflammation, impacting organs like the liver, duodenum, and heart, particularly due to a high-fat diet in rats.
The study involved three groups of rats: a control group, a high-fat diet group, and a high-fat diet group supplemented with curcumin, examining changes in glucose, insulin levels, and histological conditions.
Results showed that the high-fat diet caused significant biochemical abnormalities and inflammation, while curcumin treatment notably improved these conditions, suggesting its potential as a therapeutic agent against obesity-related complications.