Publications by authors named "Abbey Hinds"
Spine (Phila Pa 1976)
March 2019
Article Synopsis
- The study utilizes RNA in situ hybridization (RISH) to investigate the long noncoding RNA (lncRNA) Klhl14as in the development of the intervertebral disc (IVD) in mouse embryos, particularly focusing on loss-of-function mutations in key transcription factors (TFs).
- The objective is to validate Klhl14as within the developing IVD, as understanding its role can help clarify the complex processes behind IVD formation, which is significant for regenerative medicine.
- Results indicate that Klhl14as expression is notably influenced by specific transcription factors, suggesting its important role in the gene regulatory network involved in axial skeleton development.
