Vitagnus an estrogen-riched herbal remedy used in sexual dysfunction: A randomized clinical trial.

Background: Sexual dysfunction is a common problem in the postmenopausal period. Vitagnus is a phytoesterogen containing herb, which can bind to estrogen receptors and modulate their function. In this study, we evaluated the efficacy of oral vitagnus solution on sexual dysfunction improvement among postmenopausal women in North Khorasan Province, Iran.

Comparison of Perceived Self-efficacy, Benefits, and Barriers of Hypertension Control between Male and Female Patients Referred to Rajaie Cardiovascular Medical and Research Center in Tehran.

Background: Hypertension is a health problem. The purpose of the present study was to compare perceived self-efficacy, benefits, and barriers of hypertension control between male and female patients.

Methods: This cross-sectional study was carried out on 400 patients referred to Rajaie Cardiovascular Medical and Research Center in Tehran from August 2020 through March 2021.

Vaccination and isolation based control design of the COVID-19 pandemic based on adaptive neuro fuzzy inference system optimized with the genetic algorithm.

The study of the COVID-19 pandemic is of pivotal importance due to its tremendous global impacts. This paper aims to control this disease using an optimal strategy comprising two methods: isolation and vaccination. In this regard, an optimized Adaptive Neuro-Fuzzy Inference System (ANFIS) is developed using the Genetic Algorithm (GA) to control the dynamic model of the COVID-19 termed SIDARTHE (Susceptible, Infected, Diagnosed, Ailing, Recognized, Threatened, Healed, and Extinct).

Long-term follow-up of intracerebroventricular injection of streptozotocin-inducing pain sensitization.

Age is known to be the major risk factor for both pain sensation and sporadic Alzheimer's disease (sAD). Pain management in AD is a critical health condition. However, assessing pain in sAD patients is challenging.

Effect of Participatory Care Model on Postpartum Quality of Life and Performance During the COVID-19 Pandemic.

Objectives: Postpartum services are the most important factor in preventing unwanted maternal and neonatal outcomes. Considering the COVID-19 pandemic and the stress associated with the risk of infection, one way to improve midwifery services in the postpartum period and reduce unwanted maternal and neonatal outcomes is the participatory care model. Therefore, we aimed to assess the effect of the participatory care model on quality of life and performance in the postpartum period.

Optimal Allocation of Vaccine and Antiviral Drugs for Influenza Containment over Delayed Multiscale Epidemic Model considering Time-Dependent Transmission Rate.

In this study, two types of epidemiological models called "within host" and "between hosts" have been studied. The within-host model represents the innate immune response, and the between-hosts model signifies the SEIR (susceptible, exposed, infected, and recovered) epidemic model. The major contribution of this paper is to break the chain of infectious disease transmission by reducing the number of susceptible and infected people via transferring them to the recovered people group with vaccination and antiviral treatment, respectively.

Postpartum care promotion based on maternal education needs: A mixed study.

Background: The postpartum period can be considered as one of the most sensitive stages of life in different countries; however, it is inadequate in many developed and developing countries. We aimed to determine the educational needs of mothers in the postpartum period in Bojnourd.

Materials And Methods: This study was conducted in Bojnourd 2019 with two parts: a qualitative part using the content analysis method and a quantitative part using the descriptive cross-sectional method.

A Neonatal Mild Defect in Brain Insulin Signaling Predisposes a Subclinical Model of Sporadic Alzheimer's to Develop the Disease.

Brain insulin system dysfunction has been proposed as a key player in the pathogenesis of sporadic Alzheimer's disease (sAD). Given this fact, an adult rat model for sAD has been developed by intracerebroventricular injection of a subdiabetogenic streptozotocin dosage (icv-STZ). A low dose of icv-STZ in adult rats leads to a subclinical model of Alzheimer's disease.

Parameter Estimation and Prediction of COVID-19 Epidemic Turning Point and Ending Time of a Case Study on SIR/SQAIR Epidemic Models.

In this paper, the SIR epidemiological model for the COVID-19 with unknown parameters is considered in the first strategy. Three curves (, , and ) are fitted to the real data of South Korea, based on a detailed analysis of the actual data of South Korea, taken from the Korea Disease Control and Prevention Agency (KDCA). Using the least square method and minimizing the error between the fitted curve and the actual data, unknown parameters, like the transmission rate, recovery rate, and mortality rate, are estimated.

Optimal Control Design of Impulsive SQEIAR Epidemic Models with Application to COVID-19.

This paper presents a SEIAR-type model considering quarantined individuals (Q), called SQEIAR model. The dynamic of SQEIAR model is defined by six ordinary differential equations that describe the numbers of Susceptible, Quarantined, Exposed, Infected, Asymptomatic, and Recovered individuals. The goal of this paper is to reduce the size of susceptible, infected, exposed and asymptomatic groups to consequently eradicate the infection by using two actions: the quarantine and the treatment of infected people.

The Effect of Prenatal Self-Care Based on Orem's Theory on Preterm Birth Occurrence in Women at Risk for Preterm Birth.

Background: Preterm birth is increasing as a major cause of perinatal complications and mortality in Iran. The present study aimed to investigate the effect of prenatal self-care based on Orem's theory on preterm birth occurrence in women at risk for preterm birth.

Materials And Methods: The present clinical trial was conducted on 176 pregnant women at 24-26 weeks at risk for preterm birth in Mashhad, Iran, from December 2015 to October 2016.

Observer-based adaptive PI sliding mode control of developed uncertain SEIAR influenza epidemic model considering dynamic population.

This paper presents a new Susceptible, Exposed, Infected, Asymptomatic, and Recovered individuals (SEIAR) model for influenza considering a dynamic population. In the given model, the possibility of transmission of asymptomatic individuals (infectious with no visible symptoms) to infected individuals (infectious exhibiting symptoms) is considered. The basic reproduction number and the equilibrium points of the new model are given while the stability of the equilibrium points is analyzed by using the Jacobian matrix.

A Highly Selective DNA Sensor Based on Graphene Oxide-Silk Fibroin Composite and AuNPs as a Probe Oligonucleotide Immobilization Platform3667.

In this study, a simple and novel electrochemical biosensor based on a glassy carbon electrode (GCE) modified with a composite of graphene oxide (GO) - silk fibroin nanofibers (SF) and gold nanoparticles (MCH/ssDNA/AuNPs/SF/GO/GCE) was developed for detection of DNA sequences. The fabrication processes of electrochemical biosensor were characterized by scanning electron microscopy (SEM), FT-IR and electrochemical methods. Some experimental conditions such as immobilization time of probe DNA and MCH incubation time, time and temperature of hybridization were optimized.

A transient insulin system dysfunction in newborn rat brain followed by neonatal intracerebroventricular administration of streptozotocin could be accompanied by a labile cognitive impairment.

The early postnatal period is a critical period of hippocampus development, which is highly dependent on insulin receptor (IR) signaling and very important in cognitive function. The present study was conducted in order to present a model of neonatal transient brain insulin system dysfunction through finding an appropriate dose of injection of streptozotocin (STZ) during the neonatal period. Sixty male Wistar rat pups were divided into 4 groups of 15 and received intracerebroventricular saline or STZ (icv-STZ) (15, 20 and 25μg/kg) on postnatal day 7.