Development and biochemical characterization of freeze-dried guava powder fortified with Lactobacillus plantarum.

Guava (Psidium guajava L.) is one of the most nutrient-dense fruits, which is native to tropical and subtropical regions of the world. The processing of value-added products from guava has not been carried out on a scale similar to some other fruits, which offers an opportunity to fully exploit the potential of this fruit, such as guava-based nutraceutical food products.

Assessing shade matching capability of Omnichroma, a single shade composite in posterior restorations: an in vitro study.

Recent composites are being developed to simplify shade matching in composite restorations. Only a limited amount of research has been conducted to determine the optical performance of this newly introduced composite in this area. This study investigated the Omnichroma (OMN) color matching (a single shade composite within type-I restorations) via simulated clinical cavities.

Cytokine-induced killer cells: new insights for therapy of hematologic malignancies.

Background: Cytokine-induced killer (CIK) cells are a novel subgroup of immune effectors, classified as one of the modified T cell-mediated arms for immunotherapy. These cells exert MHC-unrestricted cytotoxicity against both hematological and solid malignancies with low incidence of treatment-related severe complications. This study reviews the application of CIK cells in treating cases with hematologic malignancies.

Interactions Between Oral Microbiota and Cancers in the Aging Community: A Narrative Review.

The oral microbiome potentially wields significant influence in the development of cancer. Within the human oral cavity, an impressive diversity of more than 700 bacterial species resides, making it the second most varied microbiome in the body. This finely balanced oral microbiome ecosystem is vital for sustaining oral health.

DeepDRA: Drug repurposing using multi-omics data integration with autoencoders.

Cancer treatment has become one of the biggest challenges in the world today. Different treatments are used against cancer; drug-based treatments have shown better results. On the other hand, designing new drugs for cancer is costly and time-consuming.

Impact of Multiarterial Revascularization on Long-term Major Adverse Cardiovascular Events After Coronary Bypass in 23,798 Patients.

Background: This study evaluated the association between bypass grafting with multiarterial grafts (MAG) and single arterial grafts (SAG) and all-cause mortality and major adverse cardiovascular and cerebrovascular events (MACCE), overall and across different patient subgroups from a Middle Eastern nation.

Methods: This single-center retrospective cohort study included 23,798 patients. MAG and SAG groups were balanced using inverse probability weighting (IPW).

Surface markers on microparticles involved in obesity-derived diseases.

Aims: This review aimed to investigate the different types of microparticles playing role in obesity-related diseases. Additionally, the factors participating in changing the microparticles amount in obese people will also be discussed.

Material & Methods: The authors collected the relevant articles published until 2023 and these are carefully selected from three scientific databases based on keywords.

HGTDR: Advancing drug repurposing with heterogeneous graph transformers.

Motivation: Drug repurposing is a viable solution for reducing the time and cost associated with drug development. However, thus far, the proposed drug repurposing approaches still need to meet expectations. Therefore, it is crucial to offer a systematic approach for drug repurposing to achieve cost savings and enhance human lives.

Trophic transfer, bioaccumulation and translocation of microplastics in an international listed wetland on the Montreux record.

Microplastics (MPs) are concerning emerging pollutants. Here, MPs in four edible aquatic species of different trophic levels (between ∼2 and 4), including fish species Esox lucius (Esocidae: Esocinae); Cyprinus carpio (Cyprinidae: Cyprininae); and Luciobarbus caspius (Cyprinidae: Barbinae); and the swan mussel Anodonta cygnea (Unionidae), were assessed in the Anzali freshwater ecosystem. It is a listed wetland in the Montreux record.