Background: Amongst the chemical warfare agents, blistering (vesicant) agents can be significant materials. The most important agent in this group is sulfur mustard (mustard gas) which is known as "King of chemical warfare (CW) agents ". Exposure to this agent, seriously causes damages in several organs, such as the eyes.
View Article and Find Full Text PDFIntroduction: Oxidative stress is a common factor in cataract. Considering the antioxidant properties of hesperidin as a flavanone glycoside from the flavonoid family with radioprotective effect, this study aimed to determine the protective effect of this flavanone glycoside on reducing oxidative stress in the eye lens tissue of mature rats caused by gamma irradiation.
Materials And Methods: A total of 48 adult rats were randomly divided into six groups, namely, control, Dimethyl sulfoxide (DMSO), hesperidin, radiation, radiation + DMSO, and radiation + hesperidin.
Context: Mycotoxins are secondary metabolites produced by certain toxigenic fungi and the most of them are aflatoxins, fumonisins, trichothecenes, ochratoxin A, patulin, and zearalenone.
Evidence Acquisition: In consideration of the consumption of certain farm products for animal feed and the prevalence of toxigenic fungi and mycotoxins in food, the present study was performed to evaluate this situation in Iran with a review of the literature using search engines. All published articles were selected using Iran Medex, Magiran, PubMed NCBI, and Google Scholar.
As a well-known organophosphate insecticide, diazinon (DZN) has been used for several decades in agriculture. The major signs of ophthalmic toxicity of DZN have been reported to be cholinergic overstimulation (lacrimation, myosis). Here, we report, for the first time, ulcerative keratitis in C57bl/6 mice secondary to sub-acute exposure to DZN.
View Article and Find Full Text PDFBackground And Aims: Valvular atherosclerosis is defined as extra- and intracellular lipid deposition, thickening of the fibrosa layer, decreased thickness of the spongiosa, and chronic inflammation. We sought to identify the predictive factors for valvular atherosclerosis and assess the possible associations between valvular atherosclerosis and coronary atherosclerosis using the Gensini score.
Methods: Between January 2004 and May 2008, 1400 adult patients underwent mitral or aortic valvular surgery with or without coronary artery bypass grafting (CABG) at our center.