Publications by authors named "Abbas Shakoori-Farahani"
Background: LncRNA PCAT-1 is known to promote cancer proliferation, invasion, and metastasis. However, its significance in HNSCC is not fully understood. This research investigates how the PCAT-1 / miR-145-5p / FSCN-1 axis promote HNSCC.
View Article and Find Full Text PDFBackground & Aim: The histologic and molecular changes from intestinal metaplasia (IM) to gastric cancer (GC) have not been fully characterized. The present study sought to identify potential alterations in signaling pathways in IM and GC to predict disease progression; these alterations can be considered therapeutic targets.
Materials & Methods: Seven gene expression profiles were selected from the GEO database.
Investigating the role of circulating tumor cells (CTCs) and their characteristics is still controversial in patients with gastric cancer (GC). Therefore, in this study, to provide a comprehensive review and meta-analyses of the literature on association of CTCs with gastric cancer, Scopus, Web of Science, Embase, and Medline were searched for systematic reviews and meta-analyses conducted during February 2022 using the keywords. Risk of bias, hazard ratios (HRs), and risk differences (RD) were assessed.
View Article and Find Full Text PDFIntroduction: Gastritis is among the most common human diseases worldwide. Although the involvement of Helicobacter pylori infection as a class I human carcinogen for gastric cancer progression is accepted, it is not well known how gastritis progression to atrophy and stomach cancer occurs. In this case-control study, the potential link of H.
View Article and Find Full Text PDFEvaluation of Acinetobacter baumannii, Klebsiella pneumoniae, and Staphylococcus aureus respiratory tract superinfections among patients with COVID-19 at a tertiary-care hospital in Tehran, Iran.
Eur J Med Res
September 2023
Article Synopsis
- A study found that a high percentage (83.16%) of ICU COVID-19 patients experienced healthcare-associated infections (HAIs), mostly caused by bacteria like Klebsiella pneumoniae and Acinetobacter baumannii.
- Significant mortality and intubation rates were linked to these superinfections, with specific predictors identified, highlighting the critical role of antibiotic management.
- The research underscored the urgency for tailored antibiotic treatment strategies and improved infection control practices in healthcare settings to combat these resistant infections.