Publications by authors named "Abbas R Foroushani"

Article Synopsis
  • * The researchers tested the new Cs/PF/MTF formulation's effectiveness against both the parasite stages in vitro and in vivo on naturally infected dogs, finding it significantly more potent than standard miltefosine.
  • * The new formulation was well-tolerated in dogs, with successful intravenous doses of 170 μg/kg administered daily for 28 days, indicating potential for improved treatment outcomes in CVL.
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  • - The study explored the long-term effects of bladder neck incision (BNI) and valve ablation on kidney and bladder function in children with posterior urethral valves (PUV) and bladder neck hypertrophy (BNH), involving 301 patients over a 5-year follow-up period.
  • - Results showed significant improvements: hydronephrosis cases dropped from 88.3% to 24.3% and vesicoureteral reflux (VUR) from 62.5% to 6.6%, indicating enhanced bladder and renal function post-surgery.
  • - The findings suggest that simultaneous BNI and valve ablation can particularly benefit children with PUV and BNH, improving urodynamic and
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Background And Purpose: The seroprevalence of antibodies against measles, mumps, and rubella (MMR) was evaluated 17 years following a mass vaccination campaign in individuals aged 2 to 22 years who had received routine immunization but were not eligible for an extended immunization program.

Methods: Samples were acquired from Iran's National Measles Laboratory (NML), with individuals showing positive IgM results excluded. Out of the samples collected in 2020, a random selection of 290 serum samples was chosen, representing individuals between the ages of 2 and 22 years from diverse regions in the country.

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Background: Mistreatment during childbirth is a growing concern worldwide, especially in developing countries, such as Iran. In response, we launched a comprehensive implementation research (IR) project to reduce mistreatment during childbirth and enhance positive birth experiences in birth facilities. This study identified the challenges of implementing a multi-level intervention to reduce mistreatment of women during childbirth using the Consolidated Framework for Implementation Research (CFIR).

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Background And Purpose: Mental health disorders are a growing concern worldwide, with a significant impact on public health. Understanding attitudes toward seeking professional psychological help is essential in addressing these issues. In the Iranian context, there is a need for a reliable tool to measure these attitudes.

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Background: We aimed to verify the susceptibility of , and , to commercial lectins in order to identify the three species.

Methods: The degree of agglutination was determined both macroscopically and microscopically and was scored negative (-) to positive (from 1- 4) based on their percentage of agglutination.

Results: Jacalin and UEA-1 were capable of agglutination of isolates in both logarithmic and stationary phases at a concentration of 1000 μg/ml (100%).

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Objectives: This study aims to provide a systematic review and meta-analysis of the literature on The Effect of Web-Based Educational Interventions on Mental Health Literacy, Stigma and Help-seeking intentions/attitudes in young people.

Methods: Articles in English published between April 1975 and February 2023 were retrieved from seven databases, leading to a total of 2023 articles identified.

Results: 20 studies were included after applying exclusion criteria, 10 of which were eligible for meta-analysis.

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Background: Long-term use of proton pump inhibitors (PPIs) can increase the risk of gastric cancer in Helicobacter pylori-infected patients; nevertheless, there is no data about their impact on the pathogenicity of H. pylori. This study aimed at investigating the transcriptional alteration of key gene mediators of cytotoxin-associated gene-pathogenicity island (cag-PAI) among clinical H.

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Background: Cervical cancer represents one of the most prevalent cancers among women worldwide, particularly in low- and middle-income nations. Oncolytic viruses (OVs) can infect cancer cells selectively and lethally without harming normal cells. Respiratory syncytial virus (RSV) is an oncolytic virus for anticancer therapy because of its propensity to multiply within tumor cells.

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Background: Leishmaniasis is currently considered a re-emerging or emerging infection based on the geographic region. The outcome of leishmaniasis vastly depends on host interaction. This preliminary study aimed to show the association of human leukocyte antigen (HLA) class I and II genes with healed and non-healed cutaneous leishmaniasis (CL), and symptomatic and asymptomatic visceral leishmaniasis (VL) compared with control groups in Iran.

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Background: Mistreatment during labour and childbirth is a common experience for many women around the world. This study aimed to explore the manifestations of mistreatment and its influencing factors in public maternity hospitals in Tehran.

Methods: A formative qualitative study was conducted using a phenomenological approach in five public hospitals between October 2021 and May 2022.

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Introduction: Effective communication is an important issue in patient-doctor interaction which is even more important regarding chronic disorders which need a strong relationship between patient and clinician for better compliance and optimal control disease.

Objectives: This study was aimed to develop the best cultural adapted Persian version of the 28-item Calgary- Cambridge Observation Guide (CCOG) questionnaire.

Methods: In this descriptive-analytic study, data collected from 400 patients attending the outpatient dermatology clinics of 3 major hospitals in Tehran using the modified Persian version of CCOG questionnaire, both before and after being visited by dermatologists.

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Background: More than half of diabetics' in Ethiopia live undiagnosed, and the majority of those who already knew their status also struggle to manage their diseases. However, the underlying challenges are less understood in the study area. Therefore, this study aimed to assess diabetes screening and management capabilities, barriers, and opportunities in southern Ethiopia.

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Thermal stress has a direct effect on various types of DNA damage, which depends on the stage of the cell cycle when the cell is exposed to different climate conditions. A literature review was conducted to systematically investigate and assess the overall effect of heat stress and DNA damage following heat exposure. In this study, electronic databases including PubMed, Scopus, and Web of Science were searched to find relevant literature on DNA damage in different ambient temperatures.

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Background: Censorship is the primary challenge in survival modeling, especially in human health studies. The classical methods have been limited by applications like Kaplan-Meier or restricted assumptions like the Cox regression model. On the other hand, Machine learning algorithms commonly rely on the high dimensionality of data and ignore the censorship attribute.

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Article Synopsis
  • The study examined how cancer rates in Iran affect catastrophic health expenses (CHE), focusing on variations across provinces and over time from 2011 to 2016.
  • A Bayesian hierarchical model was created to analyze the relationship between CHE and factors like cancer incidence, unemployment, and income equity, utilizing data from the Household Income-Expenditure Survey.
  • Findings indicate that cancer incidence, unemployment, and income inequality significantly influence CHE, suggesting that new policies are needed to alleviate financial burdens on cancer patients and address associated economic issues.
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Titanium dioxide (nano-TiO) is used abundantly in various industrial products and novel medical therapies. In addition, the impact of climate change on the health and safety will undoubtedly increase in the future. However, the effects of exposure to these nanoparticles and heat stress on hippocampal DNA damage and apoptosis remain unclear.

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Background: The loads of Chlamydia trachomatis (CT), Mycoplasma hominis (MH), and Ureaplasma urealyticum (UU) may impact infertility, as well as cause risk of transmission. The quality and quantity of semen demonstrate male reproductive health. This study aimed to investigate the semen quality affected by CT, MH, and UU loads.

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Background: Tracheoesophageal voice prostheses (TVPs) have been the gold standard in rehabilitation, after laryngectomy, producing faster and premier voicing towards esophageal speech. Fungal colonization shortens the device's lifetime and leads to prosthesis dysfunction, leakage, and subsequent respiratory infection. Therefore, in the current study, we aimed to investigate the fungal colonization patterns and to propose prophylactic measures that shall increase the longevity of voice prosthesis.

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Background: Invasive fungal infections (IFIs) are complications that lead to mortality and morbidity in hematologic malignancies. The time of starting antifungal therapy is vital. Preemptive antifungal therapy has appeared recently as a new policy for the management of IFIs based on noninvasive ways in neutropenic patients.

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Background: The thermal strain can be measured using subjective methods without the use of sensitive equipment. The purpose of the present study was the development and validation of an observational - perceptual heat strain risk assessment (OPHSRA) method.

Methods: This cross-sectional study, in 2019, was performed.

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Article Synopsis
  • A novel method for detecting glioblastoma multiforme (GBM) was developed using the combination of 5-aminolevulinic acid (ALA) and iron supplements, specifically ferric ammonium citrate (FAC), evaluated through R' and quantitative susceptibility mapping (QSM).
  • In experiments with glioblastoma cells and Wistar rats, results showed significantly higher intracellular iron accumulation after sequential treatment with ALA and FAC compared to control groups.
  • The study demonstrated that this treatment not only enhanced iron deposition in glioma cells but also improved the detection capabilities of 3 T MRI for identifying GBM through increased relaxivity and magnetic susceptibility values.
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Introduction: Lifelong medical management is the main intervention to reduce diabetes-related morbidities and premature deaths; yet, social support can be a vital intervention to improve diabetics' health. Therefore, this study aimed to determine the magnitude, types, and role of social support in diabetes management in southern Ethiopia.

Methods: A multi-stage systematic sampling was applied to recruit 634 adult diabetics from the three-tiered healthcare system in the region.

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