Comparative Efficacy of Dexmedetomidine and Remifentanil in Reducing Postoperative Pain and Opioid Use: A Systematic Review.

Postoperative pain management is a critical component of patient care following surgical procedures. Opioid analgesics, particularly Remifentanil, have been traditionally used to manage pain, but these drugs come with significant risks, including opioid-induced hyperalgesia (OIH) and the potential for dependence on opioids. Dexmedetomidine, an alpha-2 adrenergic receptor agonist, is a promising non-opioid alternative.

Taste and pheromonal inputs govern the regulation of time investment for mating by sexual experience in male Drosophila melanogaster.

Males have finite resources to spend on reproduction. Thus, males rely on a 'time investment strategy' to maximize their reproductive success. For example, male Drosophila melanogaster extends their mating duration when surrounded by conditions enriched with rivals.