Publications by authors named "Abbas A Mehdi"
Purpose Fibromyalgia syndrome (FMS) presents a chronic pain condition affecting muscles and joints. Investigating circadian rhythms' disruption, integral to physiological responses, this study delves into the potential impact of gene polymorphism (rs57875989) on FMS pathogenesis. Methods In this study, we investigated gene polymorphism in 100 FMS patients and an equal number of control individuals.
View Article and Find Full Text PDFThe circadian system plays a crucial role in regulating metabolic homeostasis at both systemic and tissue levels by synchronizing the central and peripheral clocks with exogenous time cues, known as zeitgebers (such as the light/dark cycle). Our body's behavioral rhythms, including sleep-wake cycles and feeding-fasting patterns, align with these extrinsic time cues. The body cannot effectively rest and repair itself when circadian rhythms are frequently disrupted.
View Article and Find Full Text PDFArticle Synopsis
- - This study investigates the effects of flaxseed supplementation on symptoms related to perimenopausal syndrome and blood levels of polyphenol metabolites in women, highlighting the hormonal benefits of flaxseed due to its phytoestrogens.
- - A total of 145 perimenopausal women participated, with one group receiving flaxseed powder and the other a placebo of roasted wheat flour over three months; various menopausal symptoms were assessed using specialized questionnaires.
- - Results showed significant improvements in menopausal symptoms for the flaxseed group, with substantial decreases in symptom scores and significant increases in beneficial blood metabolites, while the placebo group displayed minimal changes.
Background Although knee osteoarthritis (KOA) and osteoporosis (OP) manifest distinct pathophysiologies, they share numerous similarities. These health conditions are commonly found in older individuals, particularly among women. The objective of this study is to explore the expression of micro-RNA (miRNA) 122-5p (miR-122-5p) in people affected by both KOA and OP.
View Article and Find Full Text PDFBackground: Fracture-related infections (FRI) remain a difficult consequence for orthopedic trauma patients, their relatives, the treating physicians, and the healthcare systems. Delayed fracture-related infection is an important step in the infection process that can be controlled by diagnosing and preventing it from moving to the next level. Neutrophils CD64 and CD66b were identified as sensitive indicators in the event of infection.
View Article and Find Full Text PDFPurpose: To report the oxidative stress profile in patient of Graves' ophthalmopathy and to study the effect of hormone level normalization on oxidative stress profile.
Methods: All first time reporting patients with Graves' ophthalmopathy to Department of ophthalmology CSM Medical University (erstwhile King George's Medical University) Lucknow during the period January 2006 to December 2008 formed the cohort. Before initiating treatment a proforma directed detailed history, complete ophthalmological examination and investigations were done.