Publications by authors named "Abayomi O"

Article Synopsis
  • Alzheimer's disease is the top cause of cognitive decline worldwide, and its progression is linked to neuroinflammation caused by both innate and adaptive immune cells in the brain.* -
  • The interaction between these immune cells is critical to the disease's onset and advancement, highlighting a disruption in the brain's immune balance.* -
  • The review emphasizes the role of T lymphocytes in Alzheimer's, suggesting that understanding their functions could lead to better diagnostic tools and potential immunotherapy treatments.*
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Objective: The objective of this study was to evaluate the effects of four different cooking techniques viz: boiling, grilling, microwave, and frying; on the physicochemical characteristics of camel meat.

Methods: Protein composition and their degradation as well as biochemical and textural changes of camel meat as influenced by cooking methods were investigated.

Results: The highest cooking loss (52.

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Background: To study the mental health status of patients with visual impairment in a tertiary institution in Southwestern Nigeria.

Objectives: To determine the mental health status of individuals with loss of vision in Ogbomoso and associated factors.

Methodology: A descriptive cross-sectional study.

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Background: Neurodegenerative illnesses like Parkinson's and Alzheimer's are largely caused by the accumulation of aggregated proteins. Heat shock proteins (HSPs), which are molecular chaperons, have been linked with the modulation of β-glucocerebrosidase (GCase) function encoded by GBA1 and Synucleinopathies. Herein, the chaperonic properties of African walnut ethanolic extract (WNE) in manganese-induced Parkinsonian neuropathology in the hippocampus was examined.

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Introduction: In recent times, there has been an increase in the frequency of hypertension among young people which is contributing globally to the increase in cardiovascular morbidity and mortality in adults.

Objective: The aim of this study was therefore to determine the prevalence of primary hypertension and its risk factors among apparently healthy secondary school students in Osogbo, southwestern Nigeria.

Methods: A school-based cross-sectional study of a total of 404 secondary school students in Osogbo city.

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Problem drinking, which may be more prominent among young adults, is associated with mental and physical complications. The onset, use, and abuse of alcohol may be related to personality traits such as agreeableness, neuroticism and extraversion. This study aimed to examine the relationship between personality traits and alcohol use among undergraduates in southwest Nigeria.

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Interstitial ectopic pregnancy is a rare type of tubal pregnancy that poses diagnostic challenge. It is associated with the highest risk of massive, uncontrollable bleeding and can result in uterine rupture in the second trimester. This is a rare case of unruptured interstitial ectopic diagnosed in the first trimester by ultrasonography and managed medically with systemic methrotrexate and serial ultrasound monitoring.

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Eight sandy beaches along the coastline of Qatar and four sea surface stations on the eastern coast, adjacent to Doha Bay, were surveyed between December 2014 and March 2015. Microplastics, mainly low density polyethylene and polypropylene, were found in all samples of sediments and seawater. Blue fibers, ranging between 1 and 5mm, were the dominant type of particle present.

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Article Synopsis
  • Nigeria has one of the highest maternal mortality ratios in the world, and a study by Médecins Sans Frontières in Lagos highlights alarming rates in vulnerable slums, particularly in Makoko Riverine and Badia East.
  • The study surveyed nearly 4,000 households and found a maternal mortality ratio of 1,050 per 100,000 live births and significant rates of neonatal and child mortality, influenced by factors like home births and ethnic background.
  • These findings reveal a critical need for interventions in these urban slums, as the maternal mortality rate is much higher than the state's estimated figure of 545 per 100,000 live births.
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Background: Supportive psychotherapy, in individual or group settings, may help improve surgical outcomes for women and girls living with female genital mutilation (FGM).

Objectives: To assess whether supportive psychotherapy given alongside surgical procedures to correct complications of FGM improves clinical outcomes.

Search Strategy: We searched major databases including CENTRAL, Medline, African Index Medicus, SCOPUS, PsycINFO, and others.

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Purpose: To examine the clinical outcomes of postmenopausal African American (AA) women treated with strut-adjusted volume implant brachytherapy-based accelerated partial breast irradiation for early-stage node-negative breast cancer.

Methods: From January 2011 through April 2015, a total of 50 AA patients, meeting criteria to receive APBI as defined by the National Surgical Adjuvant Breast and Bowel Project B-39 (NASBP B-39), completed treatment with the SAVI breast brachytherapy device at Howard University Hospital.

Results: 4% ipsilateral breast tumor recurrence and 2% breast cancer-specific mortality was observed.

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Few studies in Nigeria have investigated the burden of caring for elderly persons with mental illness. The aim of this study was to examine psychiatric morbidity and burden of care among caregivers of outpatients of a psychogeriatric clinic. Burden of care was evaluated with Zarit Burden Interview.

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Background: Drink driving contributes significantly to road traffic injuries. Little is known about the relationship between drink driving and other high-risk behaviors in non-Western countries. The study aimed to assess the relationship between drink driving and other risky behaviors including making phone calls, sending text messages, nonuse of protective gear, and driving against traffic.

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Background: Tardive dyskinesia is a chronic and disabling abnormal movement disorder affecting the muscles of the face, neck, tongue and the limbs. It is a common side effect of long-term antipsychotic medication use in individuals with schizophrenia and other related psychotic disorders. While there are no known effective treatments for tardive dyskinesia to date, some reports suggest that pyridoxal 5 phosphate may be effective in reducing the severity of tardive dyskinesia symptoms.

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The 4th Schizophrenia International Research Society Conference was held in Florence, Italy, April 5-9, 2014 and this year had as its emphasis, "Fostering Collaboration in Schizophrenia Research". Student travel awardees served as rapporteurs for each oral session, summarized the important contributions of each session and then each report was integrated into a final summary of data discussed at the entire conference by topic. It is hoped that by combining data from different presentations, patterns of interest will emerge and thus lead to new progress for the future.

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TaqI A polymorphism (rs1800497) has been linked to many substance use disorders but there is a shortage of data on cannabis use disorder. Nigeria has a huge burden of cannabis use disorder, prompting our investigation of the relation between cannabis use disorder and the TaqI A polymorphism among males in Lagos, Nigeria. We recruited 106 males with cannabis use disorder based on International Classification of Diseases, version 10 (ICD-10) and 98 cannabis-naive males for the study.

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Background: Communication skills are vital in clinical settings because the manner in which bad news is delivered could be a huge determinant of responses to such news; as well as compliance with beneficial treatment option. Information on training, institutional guidelines and protocols for breaking bad news (BBN) is scarce in Nigeria. We assessed the training, experience and perceived competence of BBN among medical personnel in southwestern Nigeria.

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Drug-induced dystonic reactions are common presentations to the emergency department. Two cases of acute dystonic reactions presenting as acute medical emergency illustrate the associated fatality and possibility of misdiagnosis. This case series reports two cases of medication-induced (haloperidol and metoclopramide) acute dystonic reactions presenting with torticollis, tongue protrusion, and respiratory distress which resolved with the administration of intramuscular biperiden and oxygen by facemask.

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Background: Few studies in Nigeria have investigated HIV risk behavior among persons with severe mental disorders. This study examined HIV risk behavior and associated factors among patients receiving treatment at a Nigerian psychiatric hospital.

Aim: To determine the HIV risk behavior in persons with severe mental disorders in a psychiatric hospital.

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Objective: To assess the pattern of and factors associated with outpatient clinic attendance among patients diagnosed with schizophrenia at a Nigerian psychiatric hospital.

Methods: This was a cross-sectional descriptive study of 313 consecutive outpatients with diagnosis of schizophrenia confirmed with the Structured Clinical Interview for Diagnosis (SCID). Data was collected on sociodemographics, clinic attendance, perceived social support, perceived satisfaction with hospital care and illness severity (assessed using the Brief Psychiatric Rating Scale, BPRS).

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This study aimed to measure the subjective quality of life (QOL) of Nigerian outpatients with schizophrenia and to examine its socio-demographic as well as clinical determinants. A total of 313 outpatients with schizophrenia participated in the study. Data were collected on socio-demographics, outpatient clinic attendance, perceived social support, perceived satisfaction with hospital care, medication adherence, illness severity and QOL.

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Objective: The aim of this study was to examine the relationship between alcohol use and psychological well-being among undergraduates of a Nigerian tertiary institution. The objectives included determining the prevalence and pattern of problematic alcohol use and ascertaining the association between alcohol use and some sociodemographic variables.

Method: The Alcohol Use Disorders Identification Test (AUDIT) was used to evaluate for alcohol-related problems in 443 students of a university in southwestern Nigeria.

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Background: Community-based mental health services may be impaired by stigmatization and social distance towards persons with mental illness. Little is known about the impact of education on the attitude of volunteers for mental health programmes. This study aimed to examine the effect of an educational programme on the attitude of community volunteers towards mental illness.

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