Adult sedation and analgesia in a resource limited intensive care unit - A Systematic Review and evidence based guideline.

Background: Sedation and analgesia are essential in the intensive care unit in order to promote control of pain, anxiety, prevent loss of materials, accidental extubation and improve the synchrony of patients with ventilator. However, excess of these medications leads to an increased morbidity and mortality, and thus demands protocol.

Methods: Preferred Reporting Items for Systematic Reviews and the Meta-Analysis Protocol have been used to undertake this review.