Publications by authors named "Abate A"

Tin-based perovskite solar cells offer a less toxic alternative to their lead-based counterparts. Despite their promising optoelectronic properties, their performances still lag behind, with the highest power conversion efficiencies reaching around 15%. This efficiency limitation arises primarily from electronic defects leading to self-p-doping and stereochemical activity of the Sn(II) ion, which distorts the atomic arrangement in the material.

View Article and Find Full Text PDF

Introduction: KRAS mutation the most common molecular alteration in advanced non-small cell lung cancer (NSCLC) and is associated with an unfavourable prognosis, largely due to the lack of targeted therapeutic options for the majority of the KRAS mutated isoforms. The landscape of NSCLC treatment has expanded with the introduction of immune checkpoint inhibitors (ICIs). Nonetheless, data regarding the efficacy of ICI in NSCLC patients harbouring KRAS mutations are conflicting.

View Article and Find Full Text PDF

Phototherapy is the preferred treatment for neonatal hyperbilirubinemia and has largely replaced exchange transfusions due to its effectiveness and safety. The primary aim of this study was to evaluate the time to recovery and its predictors among neonates undergoing phototherapy at the Neonatal Intensive Care Unit of the Northwest Comprehensive Specialized Hospital in Northwest Ethiopia. A multi-center institution-based retrospective follow-up study was conducted among 423 neonates admitted to the neonatal intensive care unit between September 2019 and December 2023, at Comprehensive Specialized Hospitals of Northwest Ethiopia.

View Article and Find Full Text PDF

Introduction: Deep vein thrombosis is a serious condition and a leading cause of morbidity and mortality in hospitalized patients. Studies conducted in various hospitals in Ethiopia have reported that the prevalence rates of deep vein thrombosis range from approximately 5-10% among hospitalized patients. The risk stratification of deep vein thrombosis and the identification of associated risk factors are critical for assessing deep vein thrombosis in hospital settings.

View Article and Find Full Text PDF

Dental implants are commonly employed to address edentulism, while orthodontic treatments often incorporate mini-screws to enhance tooth movement and provide stable anchorage. Both procedures are integral to modern dental practice and frequently interact in comprehensive care scenarios. While oral health professionals routinely assess patients' medical histories before procedures, undiagnosed coagulopathies, such as Von Willebrand Disease (VWD), can present significant challenges when invasive procedures are carried out, such as the insertion of implants or mini-implants.

View Article and Find Full Text PDF

Background: Although proper latrine utilization is one of the best ways to reduce the risk of infection, it remains a challenge in the majority of rural communities in developing countries such as Ethiopia. Studies have demonstrated the link between individual behavior and latrine use, but there is a paucity of evidence on individual risk perception, perceived social pressure norms, social identity, and perceived ability, which plays an indubitable role in health and behavior change, especially in rural communities.

Objective: This study aimed to identify contextual and psychosocial factors associated with latrine utilization among rural communities in Lomabosa district, Ethiopia.

View Article and Find Full Text PDF

Mixed Sn-Pb perovskites are attracting significant attention due to their narrow bandgap and consequent potential for all-perovskite tandem solar cells. However, the conventional hole transport materials can lead to band misalignment or induce degradation at the buried interface of perovskite. Here we designed a self-assembled material 4-(9H-carbozol-9-yl)phenylboronic acid (4PBA) for the surface modification of the substrate as the hole-selective contact.

View Article and Find Full Text PDF

Background: Congenital malaria is an uncommon clinical infectious disease caused by vertical transmission of parasites from mother to child during pregnancy or delivery and a positive blood smear of malaria in newborns from 24 hours to 7 days of life, associated with a high mortality rate if it is not diagnosed and treated early. We present an unusual case of a 4-day-old boy with Plasmodium vivax malaria from Gondar, Ethiopia, suspected mainly based on a positive maternal history of malaria attacks in the seventh month of gestation and cured with artemether-lumefantrine therapy. The newborn presented with a lack of sucking and a high-grade fever.

View Article and Find Full Text PDF

Background: Eight years into the Sustainable Development Goal period, Ethiopia is not on track to achieve good hygiene practices among school children. Ensuring good hygiene practices among primary school children to prevent the spread of communicable diseases remains a challenge in most primary schools in Ethiopia. Therefore, the aim of this study was to identify factors associated with hygiene practices among primary school children in southern Ethiopia.

View Article and Find Full Text PDF
Article Synopsis
  • Acute kidney injury (AKI) is a significant health issue in neonates, particularly in developing regions like Ethiopia, with this study particularly focusing on its incidence and predictors in intensive care settings.
  • A retrospective analysis of 634 neonates revealed a 14.9 per 1000 incidence rate of AKI, with various factors such as sepsis, perinatal asphyxia, and specific drug use (like gentamicin) identified as statistically significant predictors.
  • This research highlights the need for increased attention to neonatal care in low-resource settings to help reduce morbidity and mortality associated with AKI.
View Article and Find Full Text PDF
Article Synopsis
  • - Ethiopia faces high neonatal and maternal mortality rates, largely influenced by preterm prelabor rupture of membrane (PPROM), yet there's limited research on its prevalence and causes in the country
  • - A systematic review gathered data from 13 studies involving 24,386 participants, finding a pooled prevalence of 6.58% for PPROM and identifying significant risk factors like urinary tract infections, abnormal vaginal discharge, and malnutrition
  • - The findings highlight the urgent need for improved maternal health strategies in Ethiopia, given the strong links between PPROM and various health issues affecting pregnant women
View Article and Find Full Text PDF
Article Synopsis
  • * Significant risk factors associated with S. Typhi infection include not washing hands before meals, eating raw vegetables, and drinking stream water, indicating potential prevention measures.
  • * The bacteria showed high susceptibility to antibiotics with 90% effective response to ciprofloxacin, and 80% efficacy to ceftriaxone and chloramphenicol, suggesting these treatments could be effective choices for managing infections.
View Article and Find Full Text PDF

The release of pressure from a high-pressure-stable polymer/gas solution is a common method for creating gas bubbles and forming foam with a typical polyhedral cell structure. We propose a new approach to control the foaming process by pausing the bubble growth at intermediate pressure before reaching ambient pressure. This allows us to control the growth of the bubbles and investigate various physical phenomena involved in polymer foaming, such as Ostwald ripening, bubble interactions, coalescence, and different bubble growth regimes.

View Article and Find Full Text PDF
Article Synopsis
  • - The study focused on the high prevalence of gender-based violence (GBV) among refugees and internally displaced women in Africa, finding that nearly 48.2% faced such violence during emergencies.
  • - Researchers analyzed 17 studies involving over 6,000 women, utilizing various databases and statistical methods to assess the magnitude and contributing factors of GBV, identifying young age, alcohol consumption, and lack of social protection as significant risk factors.
  • - The findings highlight a critical public health issue, suggesting that interventions must focus on protecting vulnerable groups, especially younger women and those without social support in humanitarian settings.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the risk of developing anemia in older Danish individuals (aged 65 and above) who used low-dose aspirin (LDA) for cardiovascular prevention between 2008 and 2013.
  • Using Danish health registers, researchers tracked over 313,000 participants and found that LDA users had a significantly higher incidence of both hematinic deficiency (9.6%) and anemia (5.9%) compared to non-users.
  • The results suggest that approximately 6 to 10 out of every 100 older adults using LDA may develop anemia within the first five years of treatment, highlighting the risks associated with LDA usage in this demographic.
View Article and Find Full Text PDF
Article Synopsis
  • - The study focused on determining the predictors of teenage childbearing (under 20 years old) among Ethiopian women, highlighting the influence of various economic, demographic, and social factors that differ by region.
  • - Using data from the 2019 Ethiopia Demographic and Health Survey, researchers analyzed 4,712 women and found a non-random spatial distribution of adolescent childbearing, with higher risks in certain areas like Jijiga and Assosa.
  • - Findings revealed that lack of contraceptive use, being Muslim, residing in rural areas, and larger family sizes increased the risk of adolescent childbearing, while higher education, older household age, and better economic status helped reduce the risk.
View Article and Find Full Text PDF

Aim: To evaluate palatal surface effects induced by LE and RPE, alongside spontaneous changes in an untreated group, and to compare differences in canine and molar inclination among the three groups.

Materials: This randomised clinical trial aimed to compare digital models pre- and post-treatment over 12 months in patients receiving tooth-borne Leaf Expander® (LE) and tooth-borne Hyrax-type maxillary expander (RPE) treatments, alongside untreated patients. Analysis included 24 LE patients (13 males, 11 females, mean age 8.

View Article and Find Full Text PDF

Introduction: Ethiopia has one of the highest maternal death rates in the world, with 412 deaths for every 100,000 live births. A qualified healthcare professional's care during pregnancy, delivery, and the postnatal period is crucial to saving the lives of the mother and her child. The continuum of maternity health services in Ethiopia is still shallow, despite efforts to increase the use of these services.

View Article and Find Full Text PDF

Despite recent work linking mixed phenotype acute leukemia (MPAL) to certain genetic lesions, specific driver mutations remain undefined for a significant proportion of patients and no genetic subtype is predictive of clinical outcomes. Moreover, therapeutic strategy for MPAL remains unclear, and prognosis is overall poor. We performed multiomic single cell profiling of 14 newly diagnosed adult MPAL patients to characterize the inter- and intra-tumoral transcriptional, immunophenotypic, and genetic landscapes of MPAL.

View Article and Find Full Text PDF

The aim of this study was to evaluate through analysis using CBCT the transverse and axial diameters of the mandibular condyles in subjects affected by juvenile idiopathic arthritis (JIA) and compare them with those of healthy subjects. The study was conducted on CBCT scans from the digital archive of the Department of Biomedical Surgical and Dental Sciences, University of Milan, including patients with JIA and using healthy subjects as controls. Inclusion criteria: aged between 7 and 25 years old at the time of the CBCT examination; Caucasian ethnicity; diagnosis of JIA according to the International League of Associations for Rheumatology (ILAR) criteria documented in patients' records; TMJ involvement; good quality CBCTs covering our region of interest (ROI), from the glabella to the mandibular inferior border; no previous orthodontic/orthopedic treatment; no history of craniofacial trauma or congenital birth defects involving the craniofacial area.

View Article and Find Full Text PDF

Objective: The aim of this randomized controlled trial (RCT) was to evaluate the spontaneous distorotation of upper first permanent molars and the transverse dentoalveolar changes on digital casts in growing patients following maxillary expansion treatment using either the Leaf Expander® or the rapid maxillary expander (RME), both anchored to the deciduous second molar.

Trial Design And Setting: This study was a two-arm, parallel-assignment, RCT with a dual-centre design conducted at two teaching hospitals in Italy.

Participants: Inclusion criteria included maxillary transverse deficiency, prepubertal development stage (cervical vertebra maturation stage [CVMS] 1-2) and early mixed dentition with fully erupted upper first permanent molars.

View Article and Find Full Text PDF

Tin halide perovskites represent the most suitable alternative to their lead-based counterparts for sustainable photovoltaics. One of the most important drawbacks of this class of materials is the intrinsic tendency of tin (II) to oxidize under certain conditions and as a consequence of aging. Here, we explore plasma processing to gently treat the surface of the tin perovskite films.

View Article and Find Full Text PDF

Wheat is an important crop for food security, providing a source of protein and energy for the growing population in Ethiopia. However, both biotic and abiotic factors limit national wheat productivity. The availability of genetically diverse wheat genotypes is crucial for developing new wheat varieties that are both high-yielding and resilient to stress.

View Article and Find Full Text PDF

Disruption of processes involved in tissue development and homeostatic self-renewal is increasingly implicated in cancer initiation, progression, and recurrence. The adrenal cortex is a dynamic tissue that undergoes life-long turnover. Here, using genetic fate mapping and murine adrenocortical carcinoma (ACC) models, we have identified a population of adrenocortical stem cells that express delta-like non-canonical Notch ligand 1 (DLK1).

View Article and Find Full Text PDF