Childhood bacterial meningitis in Riyadh.

One hundred and six patients with culture-positive bacterial meningitis were admitted to Sulemania Children's Hospital, Riyadh, from February 1985 to July 1990. The most common organisms causing meningitis in children older than 1 month were Hemophilus influenzae type b (N = 61), Streptococcus pneumoniae (N = 19), and Neisseria meningitidis (N = 14). Among neonates, the most common organism causing meningitis was Group B beta-hemolytic Streptococcus (N = 4).

Measles vaccine failure.

Suleimania Children's Hospital, Riyadh, Saudi Arabia was the site of a on-year study, started June 1987, which was designed to investigate measles vaccine failure. The first part of the study consisted of 336 patients with measles. Diagnosis was established on clinical grounds and confirmed by fluorescent IgM analysis.

Insulin-dependent diabetes mellitus in children: Familial and clinical patterns in Riyadh.

Type I diabetes mellitus is probably common in Saudi Arabia, but only a small amount of information on the disease is available and most cases reported so far have been type II diabetes mellitus. Type I diabetes was diagnosed in 110 children who were followed at Suleimania Children's Hospital over a five-year period (1985-1989). Saudis represented 74.

Childhood diabetes in Saudi Arabia.

In Suleimania Children's Hospital, Riyadh, Saudi Arabia, 110 diabetic children were diagnosed and followed over a 5-year period (1985-1989). Seventy-five percent (82/110) were of Saudi origin and 54% (59/110) female. Their parents were often related, 31% (34/110) being first degree cousins, and 12% (13/110) second degree cousins.

Congenital adrenal hyperplasia.

The incidence of congenital adrenal hyperplasia in Saudi Arabia and the frequency of the carrier rate are not well known. Both figures should be high, considering the commonness of first-degree consanguinity in this part of the world. We present 25 cases of congenital adrenal hyperplasia, most of them due to a defect of the 21 hydroxylase enzyme, diagnosed and followed over three years at Suleimania Children's Hospital in Riyadh.

Follow-up study for measles maternal antibodies and seroconversion after measles vaccination.

Seventy-two children were included in this study which examined measles maternal antibodies in children at the ages of six and nine months. The seroconversion after the first measles vaccination at nine months and revaccination at fifteen months was also evaluated. Results of testing were negative in 33% of the children at six months and in 36% at nine months, indicating continued susceptibility to measles.

Vitamin D deficiency rickets in Riyadh.

Despite the fact that much of Saudi Arabia is sunny throughout most of the year, vitamin D deficiency rickets is not rare. Different factors are responsible for this phenomenon, especially nutritiona, social, and maternal vitamin D deficiency. We identified 500 cases of rickets out of a total of 27,236 hospital admissions, and followed at Suleimania Children's Hospital in Riyadh over three years (1986 to 1988).

Antithyroid and other organ-specific antibodies in Saudi Arab diabetic and normal children.

Sera from 162 Saudi Arab children were examined for autoantibodies to thyroid microsomes, thyroglobulin pancreatic islet cells, gastric parietal cells, and adrenocortical cells. The subjects included a control group (n = 76) and 86 children below 14 years with Type 1 diabetes. Antithyroid antibodies were detected in 8.