Seroprevalence of in a population of 15 to 35 years old in Mashhad.

Background And Objectives: is a bacterium involved in gastrointestinal disorders with a high prevalence in Iran. We have determined the seroprevalence of in the young adult population of Mashhad city for the first time.

Materials And Methods: We carried out a cross-sectional study on 933 individuals between the ages of 15 and 35 in Mashhad.

Assessing the impact of meteorological factors and air pollution on respiratory disease mortality rates: a random forest model analysis (2017-2021).

Air pollution poses a significant threat to the health of all living beings on our planet. It has been scientifically established as a crucial factor affecting mortality rates, respiratory illnesses, mental well-being, and overall health. This study aimed to investigate the impact of air pollution and meteorological factors on respiratory disease mortality rates in Mashhad in 2017-2021 using a Random Forest (RF) model.

Anomalous normal-state gap in an electron-doped cuprate.

In the underdoped n-type cuprate NdCeCuO, long-range antiferromagnetic order reconstructs the Fermi surface, resulting in a putative antiferromagnetic metal with small Fermi pockets. Using angle-resolved photoemission spectroscopy, we observe an anomalous energy gap, an order of magnitude smaller than the antiferromagnetic gap, in a wide portion of the underdoped regime and smoothly connecting to the superconducting gap at optimal doping. After considering all the known ordering tendencies in tandem with the phase diagram, we hypothesize that the normal-state gap in the underdoped n-type cuprates originates from Cooper pairing.

Reflected acoustic energy from geological layers during seismic reflection surveys.

Acoustic propagation is significantly impacted by seabed characteristics, which play a large role in propagation modeling. Shallow seabed characteristics comprise a notable area of research due to their impacts on bottom loss, but deep seabed characteristics are often ignored. At low frequencies (several hundred Hertz, particularly below 100 Hz) and at ranges less than that corresponding to the seafloor critical angle, these deep layer characteristics have non-negligible effects.

Conduit Flow Compensates for Impaired Left Atrial Passive and Booster Functions in Advanced Diastolic Dysfunction.

Background: Quantification of left atrial (LA) conduit function and its contribution to left ventricular (LV) filling is challenging because it requires simultaneous measurements of both LA and LV volumes. The functional relationship between LA conduit function and the severity of diastolic dysfunction remains controversial. We studied the role of LA conduit function in maintaining LV filling in advanced diastolic dysfunction.

Knowledge of Non-Invasive Biomarkers of Breast Cancer, Risk Factors, and BSE Practices Among Nursing Undergraduates in Farasan Island, KSA.

Background Of The Study: Mammograms are sometimes met with issues of overdiagnosis and underdiagnosis; therefore, they are less reliable in identifying cancer in women with dense breasts. As a result, it is critical to be aware of other sensitive screening techniques for the early diagnosis of breast cancer.

Aim: The ultimate objective of this study was to assess the knowledge of nursing undergraduates regarding non-invasive biomarkers, such as volatile organic compounds in breath, nipple aspirate fluid, sweat, urine, and tears, for the early detection of breast cancer to help improve patient care, determine the risk factors, and encourage practice of breast self-examination.

Awareness of sickle cell disease among nursing undergraduates in Farasan: Its interference with malaria.

Aim: The present study was conducted to generate data on awareness and incidence of sickle cell disease (SCD) and also to adduce the widespread myths peddled about SCD.

Materials And Methods: Students studying in the Department of Nursing were recruited. A pretested, self-administered sickle cell assessment questionnaire was distributed electronically through WhatsApp group to collect necessary data.

Noncoding RNAs and programmed cell death in hepatocellular carcinoma: Significant role of epigenetic modifications in prognosis, chemoresistance, and tumor recurrence rate.

Hepatocellular carcinoma (HCC) is the most common type of liver cancer with a high death rate in the world. The molecular mechanisms related to the pathogenesis of HCC have not been precisely defined so far. Hence, this review aimed to address the potential cross-talk between noncoding RNAs (ncRNAs) and programmed cell death in HCC.

Null mutants of a tomato Rho of plants exhibit enhanced water use efficiency without a penalty to yield.

Improving water use efficiency in crops is a significant challenge as it involves balancing water transpiration and CO uptake through stomatal pores. This study investigates the role of SlROP9, a tomato Rho of Plants protein, in guard cells and its impact on plant transpiration. The results reveal that SlROP9 null mutants exhibit reduced stomatal conductance while photosynthetic CO assimilation remains largely unaffected.

Radiological findings in poisoning by synthetic cannabinoids adulterated with brodifacoum.

Objectives: Severe coagulopathy due to consumption of synthetic cannabinoids adulterated with brodifacoum, a long-acting anticoagulant, is an emerging worldwide hazard. Here, we review the spectrum of imaging findings in adulterated cannabinoid poisoning.

Materials And Methods: In this retrospective study, we used the Israeli Poison Information Center database to identify patients with cannabinoid-associated coagulopathy who presented to the Rambam Health Care Campus, where most patients were treated during an outbreak in northern Israel between September 2021 and June 2022.

Association between severity of sepsis and thyroid function profile.

Background And Aim: Critical illness conditions such as sepsis are often accompanied by altered hormone levels, which may result in decreased thyroid axis activity. This condition aims to provide metabolic substrates for vital organs such as the brain and immune system. Significant alteration of the thyroid axis in critical illnesses such as sepsis known as Low-T3 Syndrome which is associated with increased mortality.

The effect of COVID-19 on Multiple Sclerosis relapse: A systematic review and meta-analysis.

Background: Multiple Sclerosis (MS) is a chronic autoimmune disease, affecting over 2.5 million people worldwide. There has been growing concern about the impact of COVID-19 on the clinical course of MS.

Distributed acoustic sensing for detecting near surface hydroacoustic signals.

Distributed acoustic sensing (DAS) is a technology that turns a fiber-optic cable into an acoustic sensor by measuring the phase change of backscattered light caused by changes in strain from an acoustic field. In October 2022, 9 days of DAS and co-located hydrophone data were collected in the Puget Sound near Seattle, WA. Passive data were continuously recorded for the duration and a broadband source was fired from several locations and depths on the first and last days.

An optimized graph-based structure for single-cell RNA-seq cell-type classification based on non-linear dimension reduction.

Background: It is now possible to analyze cellular heterogeneity at the single-cell level thanks to the rapid developments in single-cell sequencing technologies. The clustering of cells is a fundamental and common step in heterogeneity analysis. Even so, accurate cell clustering remains a challenge due to the high levels of noise, the high dimensions, and the high sparsity of data.

Distributed acoustic sensing recordings of low-frequency whale calls and ship noise offshore Central Oregon.

Distributed acoustic sensing (DAS) is a technique that measures strain changes along an optical fiber to distances of ∼100 km with a spatial sensitivity of tens of meters. In November 2021, 4 days of DAS data were collected on two cables of the Ocean Observatories Initiative Regional Cabled Array extending offshore central Oregon. Numerous 20 Hz fin whale calls, northeast Pacific blue whale A and B calls, and ship noises were recorded, highlighting the potential of DAS for monitoring the ocean.

An automated ultra-fast, memory-efficient, and accurate method for viral genome classification.

The classification of different organisms into subtypes is one of the most important tools of organism studies, and among them, the classification of viruses itself has been the focus of many studies due to their use in virology and epidemiology. Many methods have been proposed to classify viruses, some of which are designed for a specific family of organisms and some of which are more general. But still, especially for certain categories such as Influenza and HIV, classification is facing performance challenges as well as processing and memory bottlenecks.

Therapeutic effects of L-arginine, L-carnitine, and mesenchymal stem cell-conditioned medium on endometriosis-induced oocyte poor quality in an experimental mouse model.

Aim: The present study aimed to explore the potential ameliorative effects of L-arginine (LA), L-carnitine (LC), and bone marrow mesenchymal stem cell-conditioned medium (BMSC-CM) on endometriosis (EMS) model in vivo and in vitro.

Methods: The animals were divided into two main groups, normal and EMS-induced mice. Normal and EMS-induced groups were injected with or without LA (250 mg/kg), LC (250 mg/kg), and BMSC-CM (a final volume of 100 μL of CM/mouse).

PDGF and VEGF-releasing bi-layer wound dressing made of sodium tripolyphosphate crosslinked gelatin-sponge layer and a carrageenan nanofiber layer.

The use of dressings is one of the most common methods for wound treatment. Since most single-layer dressings cannot mimic the hierarchical structure of the skin well, multi-layer dressings have been considered. In this study, a bilayer dressing was fabricated using a gelatin sponge layer cross-linked with sodium tripolyphosphate (Gel-STPP) and a layer of carrageenan nanofibers containing platelet-rich fibrin (Carr-PRF).

Amikacin liposome and Mycobacterium avium complex: A systematic review.

Introduction: The prevalence of Mycobacterium avium complex (MAC) is increasing globally. Macrolide-based multidrug regimens have been recommended as the first-line treatment for patients with MAC pulmonary disease. However, developing macrolide resistance was associated with poor treatment outcomes and increased mortality.

Exploring surface source contributions to ocean ambient noise interferometry with airgun shots.

A seismic reflection survey conducted directly over two bottom-mounted hydrophones in the north-east Pacific Ocean is used to explore how surface source locations affect ambient noise interferometry for the two hydrophones. The airgun shots are used as an approximation of an impulsive sound source at a discrete location, which allows us to investigate spatial contributions to the cross correlation between the two hydrophones. Simulated and experimental results are presented.

Use, response and outcomes of second-line chemotherapy in patients with advanced biliary tract cancers.

Introduction: First-line chemotherapy for advanced biliary tract cancers has been established as gemcitabine and cisplatin; however, there is currently no recognized standard second-line chemotherapy. The purpose of this study is to review and evaluate the outcomes of second-line chemotherapy for advanced biliary tract cancers.

Methods: Patients who received chemotherapy for unresectable or metastatic biliary tract cancers at BC Cancer between August 2009 and December 2015 were retrospectively studied to identify second-line chemotherapy treatments used and to determine overall survival, time-to-treatment discontinuation and characteristics predicting for improved overall survival.