From Emotional Abuse to a Fear of Intimacy: A Preliminary Study of the Mediating Role of Attachment Styles and Rejection Sensitivity.

Based on the literature indicating that emotional abuse erodes children's secure attachment bonds, this study aimed to examine a mediation model positing that insecure attachment (anxious and/or avoidant styles) would mediate the association between childhood emotional abuse and rejection sensitivity (rejection and acceptance expectancies), which, in turn, will be associated with a fear of intimacy. One hundred and eighty members of the Israeli public aged 21-30 who were in relationships participated in the study. The results showed that avoidant and anxious attachment mediated the relationship between childhood emotional abuse and a fear of intimacy, acceptance expectancy mediated the relationship between avoidant and anxious attachment and a fear of intimacy, anxious attachment mediated the relationship between childhood emotional abuse and both rejection and acceptance expectancies, and avoidant attachment mediated the relationship between childhood emotional abuse and acceptance expectancy.

COVID-19 diagnosis on the basis of nanobiosensors' prompt interactivity: A holistic review.

The fast spread and severe consequences of novel coronavirus disease 2019 (COVID-19) have once again underscored the critical necessity of early detection of viral infections. Several serology-based techniques, including as point-of-care assays and high-throughput enzyme immunoassays that support the diagnosis of COVID-19 are utilized in the detection and identification of coronaviruses. A rapid, precise, simple, affordable, and adaptable diagnostic tool is required for controlling COVID-19 as well as for outbreak management, since the calculation and monitoring of viral loads are crucial for predicting the infection stage and recovery time.

Investigating factors affecting the development of contract farming. Case study: tomatoes in Kermanshah Province.

The escalating demands of a growing population and rising living standards strain the efficiency of traditional agricultural methods in fulfilling consumer nutritional needs. Technological advancements, particularly the introduction of contract farming models, offer a potential path towards addressing these challenges. However, in Iran, contract farming remains an underdeveloped and under-researched agricultural practice.

Subthalamic nucleus input-output dynamics are correlated with Parkinson's burden and treatment efficacy.

The subthalamic nucleus (STN) is pivotal in basal ganglia function in health and disease. Micro-electrode recordings of >25,000 recording sites from 146 Parkinson's patients undergoing deep brain stimulation (DBS) allowed differentiation between subthalamic input, represented by local field potential (LFP), and output, reflected in spike discharge rate (SPK). As with many natural systems, STN neuronal activity exhibits power-law dynamics characterized by the exponent α.

Bilateral Giant Supraclinoid Carotid Aneurysms Causing Obstructive Hydrocephalus: Case Report and Literature Review.

Intracranial aneurysms are common conditions that are usually asymptomatic and found incidentally, yet they can rupture and lead to subarachnoid hemorrhage, in addition to causing mass effects, especially with larger aneurysms. Bilateral supraclinoid aneurysms are extremely rare and were reported in only two instances. These aneurysms can cause a range of symptoms and require careful management.

Cranioplasty for Skull Defects With Polypropylene Abdominal Wall Mesh.

Objective: Cranioplasty is a well-established common surgery in the practice of neurosurgery and craniofacial surgery. In young patients, complete skull defect closure by bone splitting may be troublesome due to the difficulty to obtain enough bone area. In such cases, sometimes the authors need to use allografts, which may not be widely available in rural practice.

Mental arithmetic task detection using geometric features extraction of EEG signal based on machine learning.

Background: Mental arithmetic analysis based on electroencephalogram (EEG) signals can help to understand some disorders such as attention deficit hyperactivity disorder, arithmetic disorder, or autism spectrum disorder in which learning is difficult. Most mental computation detection and classification systems rely on the characteristics of a single channel, however, the understanding of the connections between EEG channels, which certainly contains valuable information, is still evolving. The methods presented in this paper are the result of a research project that introduces an alternative method for better and faster receipt of information from the EEG signals of individuals, which are generally complex and nonlinear.

EVALUATION OF 5-FLUOROURACIL-INDUCED CARDIOTOXICITY: ROLE OF CARDIAC BIOMARKERS.

Background: Side effects of chemotherapy in cancer patients need to be investigated in more detail.

Aim: To determine the incidence of cardiotoxicity in patients treated with different chemotherapy regimens containing 5-fluorouracil (5-FU) in Zanjan, Iran.

Patients And Methods: In a prospective cohort study, patients with different types of solid gastrointestinal tumors who were candidates for 5-FU based chemotherapy regimens were enrolled.

Cancer in Iran 2008 to 2025: Recent incidence trends and short-term predictions of the future burden.

Policymakers require estimates of the future number of cancer patients in order to allocate finite resources to cancer prevention, treatment and palliative care. We examine recent cancer incidence trends in Iran and present predicted incidence rates and new cases for the entire country for the year 2025. We developed a method for approximating population-based incidence from the pathology-based data series available nationally for the years 2008 to 2013, and augmented this with data from the Iranian National Population-based Cancer Registry (INPCR) for the years 2014 to 2016.

Extra-axial cerebellopontine angle cavernoma: A case report and review of literature.

Background: Extra-axial cavernomas at the cerebellopontine angle (CPA) are rare clinical entity that can radiologically mimic several lesions encountered at this location.

Case Description: A 36-year-old female patient referred to our emergency service with acute decreased level of consciousness and vomiting. Neurological examination showed Glasgow Coma Scale of 12 with downbeat nystagmus of the right eye.

Primary Posterior Fossa Hydatid Cyst in a Child.

A 7-year-old boy referred to our emergency department complaining of headache, nausea, vomiting, dizziness, generalized fatigue, ataxia and diplopia. Neurological exam showed bilateral papilledema and ataxic gait. Routine blood test, plain chest x-ray and abdominal ultrasonography were normal.

Cranioplasty for Skull Defect With Polypropylene Abdominal Wall Mesh.

Cranioplasty is a routine procedure in the practice in neurosurgery and craniofacial surgery. For the closure of the cranial defect, it may be difficult or impossible to split the bone sufficiently to obtain enough bone for complete closure of the defect in younger children. Thus, sometimes there is the need to use allografts, which may not be widely available in rural practice.

Castleman Disease: An Unusual Cause of an Isolated Neck Mass.

A 15-year old female patient was complaining from swelling in the left side of the neck since 3 months. Physical examination showed palpable and mobile left supraclavicular neck mass in the carotid triangle, uvula deviation to the left side and normal vocal cords position and function. Neck imagings showed well-defined, well-encapsulated left neck mass in the left carotid sheath pushing the internal jugular vein anteriorly and the common carotid artery posteriorly.

Passive artifact behavior prediction of interventional tools in high-field MRI using a 0.55T portable benchtop MR scanner.

Using magnetic resonance imaging (MRI) for guiding minimally invasive interventions requires surgical devices which on one hand are visible in the MR image but on the other hand do not generate large artifacts, which distort the overall imaging process. Passive markers are one way to visualize devices such as catheters or biopsy needles in MRI. The evaluation of newly developed passive markers usually requires access to high-field MRI scanners (1.

Distortion indicator algorithm for simple artifact assessment of passive MRI markers.

The main purpose of this work is to present a simple quantitative approach for assessing artifacts in passive instruments when used in an MRI environment. It is mainly based on a quantitative indicator related with the amount of distortion produced by the instrument on a 3D surface obtained from the 2D MR image. After a preprocessing stage for attenuation of the 3D surface low frequency components, an indicator related with the volume of the background distortion is computed for each MRI slice.

DNA Cytometry for Differentiation Between Low- and Medium-grade Dysplasia in Intraductal Papillary Mucinous Neoplasms.

Background/aim: The indication for resection of cystic pancreatic lesions is usually performed by sectional imaging criteria, such as the Sendai criteria. The aim of this study was to analyze a possible correlation between DNA cytometry and Sendai criteria for the differentiation between low-grade intraductal papillary mucinous neoplasms (IPMN-A) and medium-grade dysplasia (IPMN-B).

Materials And Methods: Histopathological analysis, DNA index and preoperative Sendai criteria were determined in 16 patients who underwent pancreatic resection for IPMN.

The DNA index as a prognostic tool in hilar cholangiocarcinoma.

Background And Objectives: Due to the devastating prognosis of patients suffering from hilar cholangiocarcinoma (HCCA) valid prognostic factors are urgently needed to guide treatment decisions in a personalized concept. The aim of this study was to analyze the predictive value of the DNA index in a large single-center cohort of patients undergoing resection of HCCA.

Methods: A total of 154 patients who underwent resection of HCCA were included in this prospective study.

Prognostic significance of DNA cytometry for adjuvant therapy response in pancreatic cancer.

Background And Objectives: The continuous progress in treatment options for pancreatic adenocarcinoma has lead to a re-evaluation of prognostic markers. In this study the prognostic relevance of DNA Index and classical histopathological parameters with regard to disease-free (DFS) and overall survival (OS) was analyzed within the CONKO-001 patient population.

Methods: One hundred forty three fresh-frozen paraffin-embedded tissue samples of the resected tumor specimen of the CONKO-001 patient population were available for DNA index analysis to evaluate its impact on patient outcome.

Benign joint hypermobility syndrome in soldiers; what is the effect of military training courses on associated joint instabilities?

Background: Hypermobile joints are joints with beyond normal range of motion and may be associated with joint derangements. This study aimed to evaluate the prevalence of benign joint hypermobility syndrome (BJHS) among soldiers and effect of training courses on related joint instabilities.

Materials And Methods: In a prospective cohort study on 721 soldiers of Iran Army in Isfahan in 2013 the prevalence of joint hypermobility was obtained by using Beighton criteria.

Patient and tumour biology predict survival beyond the Milan criteria in liver transplantation for hepatocellular carcinoma.

Background: Patients with hepatocellular carcinoma (HCC) beyond the Milan criteria are not considered for liver transplantation (LT) in many centres; however, LT may be the only treatment able to achieve long-term survival in patients with unresectable HCC. The aim of this study was to assess the role of recipient age and tumour biology expressed by the DNA index in the selection of HCC patients for LT.

Patients: Clinicopathological data of 364 patients with HCC who underwent LT between 1989 and 2010 were evaluated.

Neuronavigation-guided endoscopic endonasal resection of extensive skull base mucormycosis complicated with cerebral vasospasm.

A 24-year-old woman presented with double vision since 6 months. Examination revealed left eye ptosis and bilateral abducens nerve palsy. Brain computed tomographic scan and magnetic resonance imaging revealed a bone-eroding mass lesion located in the middle skull base, occupying the posterior ethmoidal cells, the planum sphenoidale, the sphenoid sinus, the lateral recesses of the sphenois sinus, the pterygoid apexes, and the middle and lower clivus, with compression of the inferior wall of the cavernous sinus and the parasellar and paraclival parts of the internal carotid artery.

DNA index is a strong predictive marker in intrahepatic cholangiocarcinoma: the results of a five-year prospective study.

Purpose: Predictive markers for risk stratification among patients with intrahepatic cholangiocarcinoma (IHC) are still lacking. Therefore, recent studies have focused on identifying the biological aspects of tumors that can provide more information about the tumor aggressiveness. The aim of this study was to prospectively evaluate the prognostic potential of the DNA index in patients undergoing liver resection for IHC.

The Use of Cone Beam Computed Tomography (CBCT) to Determine Supernumerary and Impacted Teeth Position in Pediatric Patients: A Case Report.

A case of a compound odontoma which caused delayed eruption of right maxillary central incisor in a ten year old girl is presented with clinical and radiographic findings. The patient presented with complaint of a hard painless swelling in the right anterior region of the maxilla and absence of right maxillary central incisor. After clinical examination, periapical and occlusal radiographs of the mentioned region were taken.

Increased T-helper 2 cytokines in bile from patients with IgG4-related cholangitis disrupt the tight junction-associated biliary epithelial cell barrier.

Background & Aims: IgG4-related cholangitis is a chronic inflammatory biliary disease that involves different parts of the pancreatobiliary system, but little is known about its mechanisms of pathogenesis. A T-helper (Th) 2 cell cytokine profile predominates in liver tissues from these patients. We investigated whether Th2 cytokines disrupt the barrier function of biliary epithelial cells (BECs) in patients with IgG4-related cholangitis.