Classifying juvenile onset primary open angle glaucoma using cluster analysis.

Aim: To classify unrelated patients with juvenile onset primary open angle glaucoma (JOAG) into clinically useful phenotypes using cluster analysis.

Methods: Out of the 527 unrelated patients with JOAG, the study included 414 patients who had all the phenotypic characteristics required for the study. A cluster analysis was performed to classify the patients based on their iris and angle morphology, age of onset, highest untreated intraocular pressure (IOP), worst mean deviation and greatest vertical cup disc ratio of the worst eye.

Refractive outcomes of cataract surgery in primary congenital glaucoma.

Aim: To evaluate refractive outcomes of cataract surgery with intraocular lens (IOL) implantation in operated eyes of primary congenital glaucoma (PCG).

Design: A retrospective case-control study.

Methods: Patients of PCG who developed cataract following trabeculectomy with trabeculotomy were recruited.

Selective laser trabeculoplasty for primary open-angle glaucoma patients younger than 40 years.

Objective: To evaluate the efficacy of selective laser trabeculoplasty (SLT) among patients with juvenile-onset primary open-angle glaucoma (JOAG).

Methods: Patients diagnosed with JOAG who were not controlled on medical therapy were offered a trial of SLT. The patients were followed up prospectively for 1, 3, 6, and 12 months postlaser to evaluate the efficacy of SLT as second-line therapy.

Steroid-induced glaucoma and childhood blindness.

Aim: To determine the prevalence, risk factors and the severity of visual loss caused by steroid-induced glaucoma (SIG) among children.

Methods: Five-year records of all paediatric glaucoma cases presenting to the glaucoma services of our tertiary care centre were evaluated. Data of children presenting with SIG were recorded with respect to their visual acuity, highest baseline intraocular pressure, cup:disc ratio, perimetry and need of glaucoma filtering surgery.