Publications by authors named "Aaysha Siddiqua"
BMC Med Genet
September 2019
Article Synopsis
- Genetic testing for breast cancer (BC) is becoming crucial for diagnosis and prevention, leading this study to investigate the effectiveness of targeted sequencing on key BC genes in a cohort from Bangladesh consisting of 52 patients.
- The study found that 25.58% of blood samples revealed clinically relevant mutations, with 13.95% showing pathogenic mutations, notably identifying five novel pathogenic mutations within the BRCA1, BRCA2, and ERBB2 genes.
- This research highlights the potential for targeted sequencing to uncover significant genetic factors related to BC, making it a valuable tool for early detection and personalized treatment in this population.
