Importance of pesticides for lethal poisoning in India during 1999 to 2018: a systematic review.

Background: Poisoning is a major problem in India. However, there is little systematic information on the key poisons responsible for most deaths by geographical area and over time. We aimed to review the literature to identify the poison classes causing the greatest number of deaths in India over the last 20 years.

Kidney function and mortality post-liver transplant in the Model for End-Stage Liver Disease era.

The Model for End-Stage Liver Disease (MELD) score incorporates serum creatinine and was introduced to facilitate allocation of orthotopic liver transplantation (LT). The objective is to determine the impact of MELD and kidney function on all-cause mortality. Among LTs performed in a tertiary referral hospital between 1995 and 2009, 419 cases were studied.

Safety and efficacy of sorafenib therapy in patients with metastatic kidney cancer with impaired renal function.

Purpose: Sorafenib is an oral Raf kinase inhibitor, approved for the treatment of advanced renal cancer. Clinical investigation of the safety and feasibility of sorafenib therapy in patients with impaired renal function was performed in this study.

Materials And Methods: The protocol was approved by the Human Investigation Committee of Wayne State University.