Publications by authors named "Aastha Ghimire"

Introduction And Importance: Erectile dysfunction (ED) resulting from pelvic trauma, particularly cavernosal artery pseudoaneurysm, poses a complex clinical challenge. Traumatic injuries, including blunt force trauma, can lead to diverse vascular complications affecting erectile function. Recognizing and addressing these issues is pivotal for optimal patient management.

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This study presents a rare case of chronic multifocal tubercular osteomyelitis in a 13-year-old boy from Nepal, a high-burden country for tuberculosis (TB). He presented with chronic pain in the lower extremities and had no pre-existing comorbidities. The patient's clinical presentation, diagnostic process, and treatment plan are described.

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Article Synopsis
  • Rhabdomyosarcoma is a rare and aggressive cancer that primarily affects children, usually under 6, resulting from immature muscle cells, and can cause non-specific symptoms like fever and bowel changes.
  • A case study highlights a 15-year-old girl diagnosed with urogenital rhabdomyosarcoma, who also presented with a rectovaginal fistula, and is currently undergoing chemotherapy, radiation, and planned surgery.
  • Early detection and a coordinated treatment approach are crucial for better outcomes in paediatric patients, as this type of cancer often displays vague symptoms that complicate timely diagnosis.
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This study presents a rare case of Rosai-Dorfman disease (RDD) with nasal and nasopharyngeal involvement, illustrating the complexities in diagnosing this enigmatic histiocytic disorder. RDD, characterized by massive, painless cervical lymphadenopathy, poses diagnostic challenges due to its diverse clinical presentations. In this case, a 38-year-old woman presented with a year-long history of neck swellings, nasal congestion, headaches, and sinusitis-like symptoms.

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Introduction And Importance: A small bowel perforation occurring in isolation as a result of blunt abdominal trauma (BAT) is a rare event, especially in pediatric patients. The unusual presentation and lack of distinct clinical indications can pose a challenge in promptly diagnosing this condition. This study seeks to underscore the importance of early detection and immediate surgical intervention when dealing with small bowel perforations following BAT.

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Background And Objectives: Esophageal and gastric fundic varices are common in liver cirrhosis patients. Ultrasound with the Doppler study assesses liver cirrhosis severity, measuring portal vein and splenic indices' association with gastroesophageal varices.

Methodology: This study was conducted on 64 subjects with sonographic features of chronic liver disease who were referred for routine follow-up scans.

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Posterior reversible encephalopathy syndrome (PRES) is a rare neuroradiological condition causing headaches, altered mental status, seizures, visual disturbances, and focal deficits. It is often associated with preeclampsia and eclampsia in pregnancy, but can also occur in patients with other medical conditions, such as hypertension, autoimmune diseases, renal dysfunction etc. This case report highlights the importance of recognizing PRES in postpartum patients with hypertension and the need for prompt diagnosis and management to prevent potential complications.

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Introduction: Tetralogy of Fallot is a cyanotic congenital heart disease which if untreated leads to death by adulthood. In rare cases who survive this can lead to secondary polycythemia due to chronic hypoxia who can present with multiple indistinct symptoms leading to diagnostic dilemma.

Case Presentation: The authors present a rare case of secondary polycythemia diagnosed in early fifties with the unique non-contrast computerized tomography head findings who presented with a spectrum of long standing symptoms and a history of neurological manifestations.

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Introduction: Duplication of the renal collecting system, known as the duplex collecting system, is a common congenital anomaly of the urinary tract. It can be partial or complete and affects 0.7-4% of the population, with a higher incidence in females.

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Introduction: Lung cancer is a major contributor of burden of disease globally. Early diagnosis plays a crucial role in determining the patient's prognosis. However, diagnostic constraints and healthcare-seeking behavior in rural areas contribute to the increased mortality and morbidity associated with this disease.

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Traumatic diaphragmatic hernia (TDH), a rare condition, often presents with diverse symptoms and can be undiagnosed for a long time. This case study underscores the significance of considering uncommon ailments, particularly in underserved regions with limited medical access. A woman with recurring epigastric pain and respiratory issues, self-treated for gastritis, was eventually diagnosed with a large diaphragmatic hernia caused by prior trauma.

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Article Synopsis
  • Metachromatic leukodystrophy (MLD) is an autosomal recessive disorder caused by a deficiency in arylsulfatase A, leading to accumulation of cerebroside sulfate and subsequent demyelination.
  • Clinical symptoms differ with age: late-infantile has rapid progression, juvenile shows slower decline, and adult-onset may present with psychiatric issues.
  • Diagnosis involves enzyme testing, imaging, and other criteria, and while there's no cure for MLD, management focuses on supportive care and potential treatments like hematopoietic stem cell transplantation.
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Unlabelled: Fahr's syndrome, also known as bilateral striatopallidodentate calcinosis is a rare neurological disorder that is characterized by abnormal deposition of calcium in the basal ganglia, cerebellar dentate nuclei, and cerebral cortical white matter. The authors report an extremely uncommon case of Fahr's syndrome with thrombocytopenia, hypoparathyroidism, and seizure.

Case Presentation: A 32-year-old male was brought with a repeated history of twitching of hands, tingling sensation, and uncontrolled seizure despite medications.

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Althoughsome medical education institutions in high-income countries have the capacity to shift education to eLearning during the COVID-19 pandemic, educational institutions in low- and middle-income countries might struggle to fully implement it. We argue for medical students to advocate for national and international collaboration in adopting technology-enhanced learning globally.

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