Identification of a novel variant in the LAMB3 gene in a patient with a distinct junctional epidermolysis bullosa laryngo-onycho-cutaneous syndrome phenotype.

Junctional epidermolysis bullosa (JEB) represents a rare mechanobullous genodermatosis, characterized by fragility and blister formation of the skin and mucous membranes. Within the JEB spectrum, laryngo-onycho-cutaneous (LOC) syndrome is a rare subtype that manifests with excess granulation tissue of the eyes, nails, skin, and larynx. Thus far, the LOC subtype has been linked predominantly to mutations in LAMA3, disrupting the epidermal basement membrane zone.

Propeller Flap Reconstruction Following Pilonidal Cyst Excision: A Single-Center Experience With Same-Day Discharge.

Introduction: Reconstruction following pilonidal cyst resection must balance risk of recurrence, healing time, and resumption of functional routine. Propeller flaps provide a reliable and effective reconstructive option. This study highlights our experience with propeller flap reconstruction following pilonidal cyst resection and demonstrates the efficacy of same-day discharge.

Dermoscopic and reflectance confocal microscopy findings in palisaded encapsulated neuroma (PEN): report of two histologically confirmed cases.

These medical case reports discuss the reflectance confocal microscopy (RCM) features of palisaded encapsulated neuromas (PEN), a relatively uncommon benign neural tumor that predominantly manifests in middle-aged females, most notably on the facial cheek. These reports feature two middle-aged females who both presented with concern for progressively enlarging cheek papules. Dermoscopy revealed the presence of symmetrical, dome-shaped papules with arborizing blood vessels that were not in sharp focus.

Characteristics of Litigations Involving Contact Dermatitis: An Exploratory Analysis.

Contact dermatitis (CD) is one of the most common skin disorders, occurring in >20% of patients worldwide. Estimated cost burden for CD in the United States approaches $1 billion annually. To describe characteristics of litigation among patients with CD.