Capillary Leak syndrome within an hour of G-CSF.

Capillary leak syndrome (CLS) is a well-known phenomenon that has been reported commonly in association with septic shock, polytrauma, and pancreatitis in intensive care settings. In the hematologic literature, it has been reported following granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor, tumor necrosis factor, interleukin 2, and interleukin 4 infusions; and autologous and allogenic bone marrow transplantations in both pediatric as well as adult populations. Only a few cases of CLS have been reported in the pediatric population following G-CSF.

Recurrent Pott Puffy Tumor in a Child With Frontonasal Dermoid: An Unusual Presentation.

We present a case of Pott puffy tumor in a 21-month-old male, the youngest patient ever reported to have developed this complication and the first ever to have developed recurrence from an infected frontonasal dermoid. Hence, by reporting this case, we want to raise awareness about the importance of early recognition of Pott puffy tumor; and the need to meticulously evaluate and resect any craniofacial dermoid that could potentially lead to recurrence and intracranial complications if left unrecognized.