Aims An in vitro evaluation of the marginal adaptation of four root canal sealer variants at the dentin-sealer and sealer gutta-percha interfaces in the coronal, middle, and apical thirds of root canals was conducted using field emission scanning electron microscope (FESEM) analysis. Materials and methods In total, 80 extracted human mandibular premolar teeth were used in this study. All teeth were decoronated to standardize the root length to 14 mm.
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