Publications by authors named "Aaron Yezbick"
Background: Augmentation of coronary perfusion may improve right ventricular (RV) failure following acute increases of RV afterload. We investigated whether intra-aortic balloon counterpulsation (IABP) can improve cardiac function by enhancing myocardial perfusion and reversing compromised biventricular interactions using a model of acute pressure overload.
Materials And Methods: In 10 anesthetized pigs, RV failure was induced by pulmonary artery constriction and systemic hypertension strategies with IABP, phenylephrine (PE), or the combination of both were tested.
Background: Monitoring tissue oxygenation (StO(2)) by visible light spectroscopy (VLS) can identify tissue ischemia, but its feasibility for detecting myocardial ischemia is not known. We hypothesized that VLS can reliably detect changes in myocardial StO(2) in pigs subjected to acute regional or global myocardial ischemia.
Methods: In 11 pigs, regional myocardial ischemia was created by ligation of left anterior descending artery (LAD).
Background: Central venous oxygen saturation (ScvO2) accurately reflects cardiocirculatory function, but is not always feasible in pediatric patients. Using an experimental and clinical approach, we determined the accuracy of a novel pediatric central venous catheter with integrated fiberoptic oximetry, correlated ScvO2 to periprocedural vital variables, and tested its feasibility in pediatric cardiac surgery patients.
Methods: In five anesthetized pigs, hemodynamics (cardiac index [CI], heart rate; mean arterial blood [MAP]; mean pulmonary artery [MPAP], central venous pressure [CVP]), fiberoptic ScvO2 (ScvO2-cath), and blood gas oximetry (ScvO2-blood) were measured during stable baseline conditions, preload reduction (caval occlusion), and dopamine infusion (5 mcg x kg(-1) x min(-1)).