Using virtual worlds for role play simulation in child and adolescent psychiatry: an evaluation study.

Aims and method To develop and evaluate a novel teaching session on clinical assessment using role play simulation. Teaching and research sessions occurred sequentially in computer laboratories. Ten medical students were divided into two online small-group teaching sessions.

Managing child and adolescent mental health problems in primary care: taking the leap from knowledge to practice.

In 2009, a conference at Imperial College London brought together experts on the primary care provision of child and adolescent mental health. The following paper highlights various themes from the conference, and particularly focuses on general practice. Despite international and national guidance, child and adolescent mental health provision in primary care is limited in the UK and globally.

A randomized, double-blind, placebo-controlled trial of donepezil hydrochloride (Aricept) for reducing the incidence of postoperative delirium after elective total hip replacement.

Objectives: This was a pilot, phase 2a study to assess methodological feasibility and the safety and efficacy of donepezil in preventing postoperative delirium after elective total hip replacement surgery in older people without pre-existing dementia. The hypothesis was that donepezil would reduce the incidence of postoperative delirium.

Methods: A double blind, placebo controlled, parallel group randomized trial was undertaken.

A systematic review comparing the functional neuroanatomy of patients with depression who respond to placebo to those who recover spontaneously: is there a biological basis for the placebo effect in depression?

Background: Functional neuroimaging research indicates that depression, and treatment, are associated with neurobiological changes. Changes associated with natural recovery or the placebo effect are unknown. The aim of this study is to assess whether the placebo effect in depression is associated with specific functional neuroimaging changes.