Publications by authors named "Aaron Nagar"

Article Synopsis
  • A study was conducted to assess a comprehensive behavior change intervention aimed at reducing unnecessary antibiotic use in hospitals by encouraging prescribers to make appropriate decisions during clinical reviews.
  • The research utilized a randomized controlled trial across multiple hospitals in the UK, tracking outcomes such as antibiotic dosage and patient mortality within 30 days post-admission through electronic health records and audits.
  • The effectiveness of the intervention was analyzed using time series methods and random-effects meta-analysis, with the study now completed and registered for validation.
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Background: We describe an outbreak of infection (CDI) with ribotype 053, a possible hypervirulent strain that causes outbreaks, in a neurosurgical unit.

Outbreak Investigation: The outbreak was investigated by creating a timeline of all toxin positive patients with root cause analysis, supplemented with ribotyping results, hand hygiene and environmental audits. There were five cases of CDI, three caused by ribotype 053 indicating transmission.

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