Publications by authors named "Aaron Mn Joiner"
Article Synopsis
- The GTPase Rab1 plays a crucial role in the early secretory pathway and autophagy, regulated by the TRAPPIII complex that activates it.
- Researchers used cryo-electron microscopy to elucidate the structure of the TRAPPIII complex when it binds to Rab1/Ypt1, revealing how they interact with membranes during activation.
- A specific part of the Trs85 subunit is essential for stable membrane binding and thus the effective activation of Rab1/Ypt1, highlighting its role as a membrane anchor in this process.
