Publications by authors named "Aaron Jun Yi Yap"
Article Synopsis
- A nationwide study was conducted to explore the link between COVID-19 mRNA vaccinations and autoimmune hepatitis (AIH), which had mostly been reported in isolated case reports.* -
- Out of 76 patients diagnosed with acute AIH between January 2019 and February 2023, only 6 women (aged 40+) developed symptoms within 42 days post-vaccination, suggesting a very low incidence.* -
- Both observed-over-expected and self-controlled case series analyses showed no statistically significant increase in AIH cases post-vaccination, indicating that COVID-19 mRNA vaccines don't appear to raise the risk for this condition, though more extensive studies are needed.*
Purpose: Bleeding is an important health outcome of interest in epidemiological studies. We aimed to develop and validate rule-based algorithms to identify (1) major bleeding and (2) all clinically relevant bleeding (CRB) (composite of major and all clinically relevant nonmajor bleeding) within real-world electronic healthcare data.
Methods: We took a random sample (n = 1630) of inpatient admissions to Singapore public healthcare institutions in 2019 and 2020, stratifying by hospital and year.