Publications by authors named "Aaron J Shiels"
The future private gastroenterology practice will be a large multidisciplinary practice including a clinic, AEC, pathology services, infusion services, anesthesia services, pharmacy services, and imaging centers. Delivery of gastrointestinal (GI) services will be a team-based clinic with AEC access and improved quality of care. Competing technologies will drive practices to promote the value of colonoscopy as the best screening test for colon cancer.
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- Current bowel prep for colonoscopies typically involves a clear liquid diet (CLD) and large laxative volumes, which can discourage patients from scheduling screenings.
- A study comparing low-residue diet (LRD) and CLD with a split dose magnesium citrate showed no significant difference in preparation quality but higher satisfaction in the LRD group.
- The findings suggest LRD is a better dietary option for patients undergoing colonoscopies, as it improves satisfaction without compromising preparation quality.
Article Synopsis
- Arginine vasopressin (AVP) is a hormone that plays a crucial role in maintaining blood pressure and is used therapeutically for hypotensive patients, but its mechanisms of action are still not fully understood.
- This study explores the hypothesis that KCNQ potassium channels mediate the vasoconstrictor effects of AVP, with specific KCNQ channels expressed in rat mesenteric artery smooth muscle cells.
- Results show that AVP suppresses KCNQ currents, leading to artery constriction, and that certain drugs can enhance or reverse these effects, indicating a complex interaction influenced by protein kinase C and calcium channels.
Background: Roux-en-Y gastric bypass is the most frequently performed bariatric surgery for morbid obesity. Gastrojejunal anastomotic strictures are a relatively frequent postoperative complication.
Objective: To evaluate the clinical outcomes and therapeutic response to through-the-scope balloon dilation performed to treat anastomotic strictures after Roux-en-Y gastric bypass surgery.