Publications by authors named "Aaron Ho-Pui Ho"
Article Synopsis
- Precise control of local heating in plasmonic nanostructures is essential for improving nanophotonic devices, but challenges still exist in understanding temperature effects on light absorption and near-field enhancement.
- The study introduces a new measurement technique that allows simultaneous observation of light absorption and near-field enhancement using advanced microscopy combined with opto-thermal analysis.
- Results showed that gold thin films demonstrate varying nonlinearity effects in near-field enhancement and light absorption, informed by a harmonic oscillation model, and these findings could enhance applications in areas like photocatalysis, photovoltaics, and surface-enhanced Raman spectroscopy.
The urgent necessity for highly sensitive diagnostic tools has been accentuated by the ongoing mpox (monkeypox) virus pandemic due to the complexity in identifying asymptomatic and presymptomatic carriers. Traditional polymerase chain reaction-based tests, despite their effectiveness, are hampered by limited specificity, expensive and bulky equipment, labor-intensive operations, and time-consuming procedures. In this study, we present a clustered regularly interspaced short palindromic repeats (CRISPR)/Cas12a-based diagnostic platform with a surface plasmon resonance-based fiber tip (CRISPR-SPR-FT) biosensor.
View Article and Find Full Text PDFObjective: The nucleic acid-based polymerase chain reaction (PCR) assay is commonly applied to detect infection with Zika virus (ZIKV). However, the time- and labor-intensive sample pretreatment required to remove inhibitors that cause false-negative results in clinical samples is impractical for use in resource-limited areas. The aim was to develop a direct reverse-transcription quantitative PCR (dirRT-qPCR) assay for ZIKV diagnosis directly from clinical samples.
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