A prospective, observational study of frailty, quality of life and dialysis in older people with advanced chronic kidney disease.

Background: Frailty is prevalent in older people with chronic kidney disease (CKD) and robust evidence supporting the benefit of dialysis in this setting is lacking. We aimed to measure frailty and quality of life (QOL) longitudinally in older people with advanced CKD and assess the impact of dialysis initiation on frailty, QOL and mortality.

Methods: Outpatients aged ≥65 with an eGFR ≤ 20ml/minute/1.