- like organism bacteremia in a user of black tar heroin.

Wound botulism due to introduction of the anaerobic bacteria, into otherwise sterile, relatively anaerobic tissue is a known complication of black tar heroin use. The treatment of wound botulism requires prompt initiation of antitoxin as well as antimicrobial therapy. We report the case of a patient with polymicrobial bacteremia that included a like organism who underwent successful treatment of their anaerobic infection with antibiotics and surgical debridement.

Biophysical analysis of HTLV-1 particles reveals novel insights into particle morphology and Gag stochiometry.

Background: Human T-lymphotropic virus type 1 (HTLV-1) is an important human retrovirus that is a cause of adult T-cell leukemia/lymphoma. While an important human pathogen, the details regarding virus replication cycle, including the nature of HTLV-1 particles, remain largely unknown due to the difficulties in propagating the virus in tissue culture. In this study, we created a codon-optimized HTLV-1 Gag fused to an EYFP reporter as a model system to quantitatively analyze HTLV-1 particles released from producer cells.